10, ISBN: 9780511904363

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR s… Mehr…

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the impo Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically å -adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis. This book will be invaluable to researchers and graduate students in academia and industry who are interested in the GPCR field. Biochemistry, Biological Sciences, G Protein-Coupled Receptors~~ Siehler, Sandra~~Biochemistry~~Biological Sciences~~9780511904363, en, G Protein-Coupled Receptors, Siehler, Sandra, 9780511904363, Cambridge University Press, 10/01/2006, , , , Cambridge University Press, 10/01/2006<

2010, ISBN: 9780511904363

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR s… Mehr…

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and. Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically -adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis. This book will be invaluable to researchers and graduate students in academia and industry who are interested in the GPCR field. eBooks, Science & Geography~~Biology, Life Sciences~~Molecular Biology, G Protein-Coupled Receptors~~EBook~~9780511904363~~Sandra Siehler, Graeme Milligan, , G Protein-Coupled Receptors, , 9780511904363, Cambridge University Press, 09/30/2010, , , , Cambridge University Press<

ISBN: 9780511904363

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs).Recent advances include the first mammalian non-rhodopsin GPCR st… Mehr…

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs).Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting.The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically -adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis.This book will be invaluable to researchers and graduate students in academia and industry who are interested in the GPCR field.; PDF; Scientific, Technical and Medical > Other branches of medicine > Pharmacology, Cambridge University Press<

ISBN: 9780511904363

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs).Recent advances include the first mammalian non-rhodopsin GPCR st… Mehr…

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs).Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting.The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically -adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis.This book will be invaluable to researchers and graduate students in academia and industry who are interested in the GPCR field.; PDF; Scientific, Technical and Medical > Other branches of medicine > Pharmacology, Cambridge University Press<

ISBN: 9780511904363

Comprehensive overview of recent discoveries, the current understanding of the biology of GPCRs and their validity as drug targets.; EPUB; Scientific, Technical and Medical > Biology, lif… Mehr…

Comprehensive overview of recent discoveries, the current understanding of the biology of GPCRs and their validity as drug targets.; EPUB; Scientific, Technical and Medical > Biology, life sciences > Biochemistry > Proteins, University of California Press<