Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the fem… Mehr…
Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2-30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs. Walter K.H. Krause, Books, Immune Infertility: The Impact of Immune Reactions on Human Infertility Books, Springer Nature<
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This book offers an overview of immune reactions inducing fertility disorders in both sexes. It discusses the nature, the origin and induction of antisperm antibodies and the role of repr… Mehr…
This book offers an overview of immune reactions inducing fertility disorders in both sexes. It discusses the nature, the origin and induction of antisperm antibodies and the role of reproductive organs and their interaction with the immune system. Health & Fitness Health & Fitness eBook, Springer Berlin Heidelberg<
Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the fem… Mehr…
Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2-30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs. Walter K.H. Krause, Books, Immune Infertility: The Impact of Immune Reactions on Human Infertility Books, Springer Nature<
- new Free shipping on orders above $25. Versandkosten:zzgl. Versandkosten.
This book offers an overview of immune reactions inducing fertility disorders in both sexes. It discusses the nature, the origin and induction of antisperm antibodies and the role of repr… Mehr…
This book offers an overview of immune reactions inducing fertility disorders in both sexes. It discusses the nature, the origin and induction of antisperm antibodies and the role of reproductive organs and their interaction with the immune system. Health & Fitness Health & Fitness eBook, Springer Berlin Heidelberg<
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This comprehensive overview of immune reactions inducing fertility disorders in both sexes first describes the nature and the function of sperm antigens which are capable to induce immune infertility as well as the methods to analyse and characterize these antigens. Secondly, the nature, the origin and induction of antisperm antibodies (ASA) in both sexes and the role of reproductive organs and their interaction with the immune system will be discussed. A large section of the book, which is most important for clinicians working in reproductive medicine, deals with the clinical impact of the immune reaction in reproductive medicine, including the methods of determination and the treatment in immune infertility. Closely related to immune infertility is the development of immune contraceptives which is also discussed.
Detailangaben zum Buch - Immune Infertility
EAN (ISBN-13): 9783642013782 ISBN (ISBN-10): 3642013783 Gebundene Ausgabe Erscheinungsjahr: 2009 Herausgeber: Springer-Verlag GmbH 236 Seiten Gewicht: 0,565 kg Sprache: eng/Englisch
Buch in der Datenbank seit 2007-01-16T23:21:21+01:00 (Berlin) Detailseite zuletzt geändert am 2018-10-24T11:59:45+02:00 (Berlin) ISBN/EAN: 9783642013782
ISBN - alternative Schreibweisen: 3-642-01378-3, 978-3-642-01378-2 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: naz, krause walter, walter kraus Titel des Buches: naz, the human impact
Daten vom Verlag:
Autor/in: Walter K.H. Krause; Rajesh K. Naz Titel: Immune Infertility - The Impact of Immune Reactions on Human Infertility Verlag: Springer; Springer Berlin 236 Seiten Erscheinungsjahr: 2009-09-09 Berlin; Heidelberg; DE Gedruckt / Hergestellt in Deutschland. Gewicht: 0,550 kg Sprache: Englisch 181,89 € (DE) 186,99 € (AT) 187,00 CHF (CH) Not available, publisher indicates OP
BB; Book; Hardcover, Softcover / Medizin/Klinische Fächer; Reproduktionsmedizin; Verstehen; Medizin, Gesundheit; infertility; treatment; assisted reproduction; Antigen; vaccine; lymphocytes; contraception; sperm antibodies; reproduction; clinical trial; immune contraception; testis; medicine; immune chemistry; fertility; Reproductive Medicine; Medicine; B; Gynecology; Urology; Immunology; General Practice / Family Medicine; Dermatology; Gynäkologie und Geburtshilfe; Urologie, Medizin des Harn- und Geschlechtsapparats; Immunologie; Allgemeinmedizin / Familienmedizin; Dermatologie; BB; BC; EA
Sperm Antigens.- Proteomics of Human Spermatozoa.- Methods of Analysis of Sperm Antigens Related to Fertility.- Sperm Surface Proteomics.- Sperm Functions Influenced by Immune Reactions.- Antisperm Antibodies (ASA).- The Immune Privilege of the Testis.- Immune Chemistry of ASA.- Sperm-Specific T Lymphocytes.- Site and Risk Factors of Antisperm Antibodies Production in the Male Population.- Biologic Substrates Containing ASA.- ASA in the Female.- Sperm-Immobilizing Antibody and Its Target Antigen (CD52).- The Clinical Impact of Sperm Antibodies.- Male Autoimmune Infertility.- Tests for Sperm Antibodies.- Impact on Fertility Outcome.- Sperm Antibodies and Assisted Reproduction.- Treatment of Immune Infertility.- Immune Contraception.- Immunization with Sperm Antigens to Induce Contraception.- Immunocontraception in Wildlife Animals.- Experience from Clinical Trials with Fertility Control Vaccines.
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