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Analysis of Protein-Protein Interactions - Sam Ansari
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2012, ISBN: 9783639414677

ID: 157193645

Revision with unchanged content. In the past years protein-protein interactions have gained a strong interest in the fields of pharmacy, medicine, biology, and bioinformatics. In this book, statistical information on protein-protein interactions are computationally collec­ted and analyzed. Characteristic properties are determined and their predictability estimated. Therefore, the results from a common docking approach are re-evaluated with the collected information to discriminate structures with high yet biologically meaningless geometric complementarity at the interface region from the near native structures. The results show that although there is a noticeable improvement in the predictability after applying statistical information, the overall accuracy is still low. To find other more specific properties, transient and permanent complexes were compared to each other. The lack of data led to an extensive search for more suitable structural data and the development of an extensive database. This database was ultimately used to retrieve a large number of protein properties that were automatically analyzed for their separation precision. A high accuracy was obtained in separating transient and permanent interactions based on the combination of only four properties. Combining this information with common docking approaches based on geometrical complementarity may lead to satisfying sensitivities. A Computational Approach Bücher > Fremdsprachige Bücher > Englische Bücher Taschenbuch 24.05.2012 Buch (fremdspr.), AV Akademikerverlag, .201

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Analysis of Protein-Protein Interactions - Sam Ansari
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Analysis of Protein-Protein Interactions - neues Buch

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Revision with unchanged content. In the past years protein-protein interactions have gained a strong interest in the fields of pharmacy, medicine, biology, and bioinformatics. In this book, statistical information on protein-protein interactions are computationally collec­ted and analyzed. Characteristic properties are determined and their predictability estimated. Therefore, the results from a common docking approach are re-evaluated with the collected information to discriminate structures with high yet biologically meaningless geometric complementarity at the interface region from the near native structures. The results show that although there is a noticeable improvement in the predictability after applying statistical information, the overall accuracy is still low. To find other more specific properties, transient and permanent complexes were compared to each other. The lack of data led to an extensive search for more suitable structural data and the development of an extensive database. This database was ultimately used to retrieve a large number of protein properties that were automatically analyzed for their separation precision. A high accuracy was obtained in separating transient and permanent interactions based on the combination of only four properties. Combining this information with common docking approaches based on geometrical complementarity may lead to satisfying sensitivities. A Computational Approach Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, AV Akademikerverlag

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Analysis of Protein-Protein Interactions - Ansari, Sam
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[ED: Softcover], [PU: Av Akademikerverlag], Revision with unchanged content. In the past years protein-protein interactions have gained a strong interest in the fields of pharmacy, medicine, biology, and bioinformatics. In this book, statistical information on protein-protein interactions are computationally collec ted and analyzed. Characteristic properties are determined and their predictability estimated. Therefore, the results from a common docking approach are re-evaluated with the collected information to discriminate structures with high yet biologically meaningless geometric complementarity at the interface region from the near native structures. The results show that although there is a noticeable improvement in the predictability after applying statistical information, the overall accuracy is still low. To find other more specific properties, transient and permanent complexes were compared to each other. The lack of data led to an extensive search for more suitable structural data and the development of an extensive database. This database was ultimately used to retrieve a large number of protein properties that were automatically analyzed for their separation precision. A high accuracy was obtained in separating transient and permanent interactions based on the combination of only four properties. Combining this information with common docking approaches based on geometrical complementarity may lead to satisfying sensitivities.164 S.Versandfertig in 3-5 Tagen

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Analysis of Protein-Protein Interactions: A Computational Approach - Sam Ansari
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Analysis of Protein-Protein Interactions
Autor:

Ansari, Sam

Titel:

Analysis of Protein-Protein Interactions

ISBN-Nummer:

9783639414677

Detailangaben zum Buch - Analysis of Protein-Protein Interactions


EAN (ISBN-13): 9783639414677
ISBN (ISBN-10): 3639414675
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2012
Herausgeber: AV Akademikerverlag

Buch in der Datenbank seit 05.01.2008 14:32:39
Buch zuletzt gefunden am 08.03.2017 00:47:00
ISBN/EAN: 9783639414677

ISBN - alternative Schreibweisen:
3-639-41467-5, 978-3-639-41467-7

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