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Integrins and Ion Channels: Molecular Complexes and Signaling  Andrea Becchetti (u. a.)  Buch  Advances in Experimental Medic  Englisch  2010 - Becchetti, Andrea
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Becchetti, Andrea:

Integrins and Ion Channels: Molecular Complexes and Signaling Andrea Becchetti (u. a.) Buch Advances in Experimental Medic Englisch 2010 - gebunden oder broschiert

2010, ISBN: 9781441960658

[ED: Gebunden], [PU: Springer US], Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a sat… Mehr…

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Integrins and Ion Channels: Molecular Complexes and Signaling  Andrea Becchetti (u. a.)  Buch  Advances in Experimental Medic  Englisch  2010 - Becchetti, Andrea
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Becchetti, Andrea:

Integrins and Ion Channels: Molecular Complexes and Signaling Andrea Becchetti (u. a.) Buch Advances in Experimental Medic Englisch 2010 - gebunden oder broschiert

2010, ISBN: 9781441960658

[ED: Gebunden], [PU: Springer US], Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a sat… Mehr…

Versandkosten:Versandkostenfrei, Versand nach Deutschland. (EUR 0.00) preigu
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ISBN: 9781441960658

Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a comple… Mehr…

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Integrins and Ion Channels Molecular Complexes and Signaling - Becchetti, Andrea und Annarosa Arcangeli
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Becchetti, Andrea und Annarosa Arcangeli:
Integrins and Ion Channels Molecular Complexes and Signaling - gebrauchtes Buch

2010, ISBN: 9781441960658

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Integrins and Ion Channels: Molecular Complexes and Signaling - Becchetti, Andrea (Herausgeber); Arcangeli, Annarosa (Herausgeber)
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Becchetti, Andrea (Herausgeber); Arcangeli, Annarosa (Herausgeber):
Integrins and Ion Channels: Molecular Complexes and Signaling - gebunden oder broschiert

2010, ISBN: 1441960651

Edition Gebundene Ausgabe Medical / Nursing, MEDICAL / General, SCIENCE / Life Sciences / Biology, Biologie, Biowissenschaften, mit Schutzumschlag neu, [PU:SPRINGER NATURE; Springer US]

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Details zum Buch
Integrins and Ion Channels: Molecular Complexes and Signaling

Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In other cases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel stimulation often controls integrin activation or expression. From a functional standpoint, studying the interplay between integrin receptors and ion channels clarifies how the extracellular matrix regulates processes as disparate as muscle excitability, synaptic plasticity and lymphocyte activation, just to mention a few. The derangement of these processes has many implications for pathogenesis processes, in particular for tumor invasiveness and some cardiovascular and neurologic diseases. This book provides a general introduction to the problems and methods of this blossoming field.

Detailangaben zum Buch - Integrins and Ion Channels: Molecular Complexes and Signaling


EAN (ISBN-13): 9781441960658
ISBN (ISBN-10): 1441960651
Gebundene Ausgabe
Erscheinungsjahr: 2010
Herausgeber: Springer-Verlag/Sci-Tech/Trade
127 Seiten
Gewicht: 0,410 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 2008-09-06T07:18:36+02:00 (Berlin)
Detailseite zuletzt geändert am 2023-06-13T13:20:06+02:00 (Berlin)
ISBN/EAN: 9781441960658

ISBN - alternative Schreibweisen:
1-4419-6065-1, 978-1-4419-6065-8
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: becchetti, remodeling communication
Titel des Buches: ion channels, molecular complexes


Daten vom Verlag:

Autor/in: Andrea Becchetti; Annarosa Arcangeli
Titel: Advances in Experimental Medicine and Biology; Integrins and Ion Channels - Molecular Complexes and Signaling
Verlag: Springer; Springer US
124 Seiten
Erscheinungsjahr: 2010-04-12
New York; NY; US
Sprache: Englisch
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
Available
XX, 124 p. 23 illus.

BB; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Medizinische Forschung; Verstehen; activation; antibody; biology; cancer; cell; development; ion channels; membrane; migration; proliferation; protein; proteins; regulation; signal transduction; tissue; Biomedical Research; EA; BC

Integrin Structure and Functional Relation with Ion Channels.- to Ion Channels.- Biochemical Methods to Study the Interactions Between Integrins and Ion Channels.- Optical Methods in the Study of Protein-Protein Interactions.- Integrins and Signal Transduction.- Physical and Functional Interaction between Integrins and hERG1 Channels in Cancer Cells.- Coordinated Regulation of Vascular Ca2+ and K+ Channels by Integrin Signaling.- Adhesion-Dependent Modulation of Macrophage K+ Channels.- Integrin Receptors and Ligand-Gated Channels.- Integrins and Ion Channels in Cell Migration: Implications for Neuronal Development, Wound Healing and Metastatic Spread.
Presents a series of essays on cellular models that have been studied Gives a brief historical background, summarizes the elements of integrin structure and outlines the main biological problems that involve signal transduction between the cell adhesion machinery and ion channels Provides a primer to the structure and physiology of the most relevant ion channel types Surveys recent views about intracellular signaling triggered by integrin activation, with special emphasis on tyrosine phosphorylation cascades and the relationship with growth factors and cytokines Reviews current technology for studying the molecular complexes formed by integral membrane proteins

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