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Novel Anticancer Drug Protocols
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Novel Anticancer Drug Protocols - neues Buch

ISBN: 9780896039636

ID: 6454430

We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy. Advances in cancer cell biology fueled by the molecular biology revolution have resulted in the uncovering of many novel potential molecular targets for cancer therapy. We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy. Advances in cancer cell biology fueled by the molecular biology revolution have resulted in the uncovering of many novel potential molecular targets for cancer therapy. New anticancer drug discovery and development is now largely focused on exploiting these new molecular targets, which encompass oncogenes, tumor s- pressor genes, and their gene products, as well as targets involved in tumor angiogenesis, metastasis, survival, and longevity mechanisms. Exploitation of some of these targets has already yielded fruits and introduced new paradigms of molecularly targeted cancer therapy into the clinic, namely, protein kinase in- bition by antibodies or small molecules, exemplified by Herceptin(R) (trastuzumab), a humanized antibody targeted against the HER-2 growth factor receptor tyrosine kinase for the treatment of metastatic breast cancer; and Gleevec, a small molecule bcr-abl kinase inhibitor for the treatment of chronic myel- enous leukemia. Books, Medical~~Clinical & Internal Medicine~~Diseases & Disorders, Novel Anticancer Drug Protocols~~Book~~9780896039636, , , , , , , , , ,, [PU: Humana Press]

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NOVEL ANTICANCER DRUG PROTOCOLS (METHODS IN MOLECULAR MEDICINE), VOLUME 85 - BUOLAMWINI JOHNK, ET AL
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Novel Anticancer Drug Protocols - John K. Buolamwini; Alex A. Adjei
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Details zum Buch
Novel Anticancer Drug Protocols

This book not only surveys the whole arena of novel anticancer drug targets, but also presents a wide-ranging selection of cutting-edge techniques currently being applied throughout novel antitumor drug discovery and development. The methods are applied to experiments involving such topics as immunotherapy, angiogenesis, cancer metastasis, the cell cycle, signal transduction inhibitors, apoptosis, antibodies, antisense molecules, microarray gene expression, flow cytometry, and PET imaging for cancer target validation. There are also proven methods for the preclinical identification of drug targets and for target validation during the clinical trials of novel agents.

Detailangaben zum Buch - Novel Anticancer Drug Protocols


EAN (ISBN-13): 9780896039636
ISBN (ISBN-10): 0896039633
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2007
Herausgeber: SPRINGER VERLAG GMBH
376 Seiten
Gewicht: 0,721 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 02.02.2008 02:34:26
Buch zuletzt gefunden am 13.08.2017 11:56:57
ISBN/EAN: 9780896039636

ISBN - alternative Schreibweisen:
0-89603-963-3, 978-0-89603-963-6


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