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Industrialization Of Drug Discovery
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The drug discovery and development process is getting longer, more expensive, and no better. The industry suffers from the same clinical attrition and safety-related market withdrawal rates today as it did 20 years ago. Industrialization of Drug Discovery: From Target Selection Through Lead Optimization scrutinizes these problems in detail, contrasting the promise of technology and. The drug discovery and development process is getting longer, more expensive, and no better. The industry suffers from the same clinical attrition and safety-related market withdrawal rates today as it did 20 years ago. Industrialization of Drug Discovery: From Target Selection Through Lead Optimization scrutinizes these problems in detail, contrasting the promise of technology and industrialization with the challenges of using the tools available to their best advantage. The book explores early successes, examines the current state of the art, and provides a strategic analysis of the issues currently facing drug discovery. Introducing the historical background and current status of the industry, the book delineates the basic tenets underlying modern drug discovery, how they have evolved, and their USE in various approaches and strategies. It examines, in detail, the regulations, requirements, guidelines, and draft documents that guide so many FDA actions. The editor devotes the remainder of the discussion to industrialization, compound and knowledge management functions, the drug screening process, collaboration, and finally, ethical issues. Drawing on real-life, from-the-trenches examples, the book elucidates a new approach to drug discovery and development. This modern-day, back-to-basics approach includes three steps: understand the science, unravel the story, and then intelligently apply the technology, bringing to bear the entire armamentarium of industrialization techniques, not just automation, to the discovery process. Using these steps, you can meet the goals of more specific targets, more selective compounds, and decreased cycle times. In effect, you can look for a bigger needle in a smaller haystack. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry. Books, Technology, Engineering and Agriculture~~Industrial Chemistry & Manufacturing Techologies~~Industrial Chemistry, Industrialization Of Drug Discovery~~Book~~9780824723910, , , , , , , , , ,, [PU: Marcel Dekker]

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Industrialization of Drug Discovery - Handen, Ph.D., Jeffrey S.
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Drug Discovery in the Modern Age: How We Got Here and Where Do We Go? J.S. Handen The Regulatory Age, S. Weinberg Industrialization Not Automation, T. Peakman Compound Management, E. Perakslis and T. Iorns High-Throughput Screening, M. Beggs, V. Emerick and R. Archer Parallel Lead Optimization, S.L. Gallion, A. Beresford, and P. Bey Knowledge Management, B. Buckta Understanding the Value of Research, P. Bussey, J. Pisani, and Y. Bonduelle Collaboration in a Virtual and Global Environment, J. Barrett From Genome to Drug: Ethical Issues, D. Magnus and P. Deverka Technology Technology eBook, CRC Press

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Industrialization of Drug Discovery: From Target Selection Through Lead Optimization - Handen, Jeffrey S. , PH. D. Handen, Handen S.
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[ED: Hardcover], [PU: MARCEL DEKKER INC], This modern-day, back-to-basics approach includes three steps: understand the science, unravel the story, and then intelligently apply the technology, bringing to bear the entire armamentarium of industrialization techniques, not just automation, to the discovery process. Using these steps, you can meet the goals of more specific targets, more selective compounds, and decreased cycle times. In effect, you can look for a bigger needle in a smaller haystack.600 pagesVersandfertig in über 4 Wochen, [SC: 0.00]

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Indization of Drg Disc 1st Edition - Jeffrey S. Handen
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Indization of Drg Disc 1st Edition Author :Jeffrey S. Handen 9780824723910 0824723910, [PU: Marcel Dekker]

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2005, ISBN: 9780824723910

ID: 6359998

Hardcover, Buch, [PU: Marcel Dekker Inc]

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Details zum Buch
Industrialization of Drug Discovery: From Target Selection Through Lead Optimization
Autor:

Handen, Jeffrey S. , PH. D.; Handen, Handen S.

Titel:

Industrialization of Drug Discovery: From Target Selection Through Lead Optimization

ISBN-Nummer:

The pharmaceutical industry suffers from an innovation deficit, with clinical attrition and safety-related market-withdrawal rates at the same level as twenty years ago. This book scrutinizes this problem in detail, contrasting the promise of technology and industrialization with the apparent inability of industry to fully realize the tools that are available. The text begins by introducing the evolution of modern drug discovery, tracing it from basic concepts to current approaches. The editor devotes the remainder of the discussion to the regulatory environment, industrialization, compound and knowledge management functions, the drug screening process, collaboration, and finally, ethical issues.

Detailangaben zum Buch - Industrialization of Drug Discovery: From Target Selection Through Lead Optimization


EAN (ISBN-13): 9780824723910
ISBN (ISBN-10): 0824723910
Gebundene Ausgabe
Erscheinungsjahr: 2005
Herausgeber: MARCEL DEKKER INC
328 Seiten
Gewicht: 0,594 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 24.10.2007 20:36:17
Buch zuletzt gefunden am 08.03.2017 16:43:45
ISBN/EAN: 9780824723910

ISBN - alternative Schreibweisen:
0-8247-2391-0, 978-0-8247-2391-0


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