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Technological and Medical Implications of Metabolic Control Analysis - Springer
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Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex­ pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta­ bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio­ technologists can only ignore these topics at their peril. Proceedings of the NATO Advanced Research Workshop, Visegrád, Hungary, 10-16 April 1999 Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer

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[ED: Hardcover], [PU: Springer Netherlands], Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril. xiv, 374 S. 82 SW-Abb. 244 mm Versandfertig in 3-5 Tagen, [SC: 0.00], Neuware, gewerbliches Angebot

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Technological and Medical Implications of Metabolic Control Analysis
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The study of multienzyme systems has advanced considerably during the least decade. The cell is more complicated than classical biochemistry presents it, it contains more structure, and the behaviour of any system of enzymes is more elaborate than can be explained in simple terms. Nevertheless, classical enzymology and metabolism remain central to any modification of the metabolic behaviour of organisms, as attempted by modern biotechnology and drug development techniques. In this cool, objective look at the current state of the art, internationally respected authors draw attention to the drawbacks, problems, and opportunities associated with this exciting field. The areas covered include problems with current practice, the imposition of human objectives on organisms, understanding health and disease, computer modelling, the increasingly complex picture of cell structure, control and regulation of metabolism, and the general contribution metabolic control is making to biochemistry on a broader canvas. Books, Health and Well Being, Technological and Medical Implications of Metabolic Control Analysis Books>Health and Well Being, Springer Netherlands

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Technological and Medical Implications of Metabolic Control Analysis - Athel Cornish-Bowden; Maria Luz Cárdenas
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Medicine & Public Health; Internal Medicine; Biochemistry, general; Cancer Research; Mathematical and Computational Biology behavior, biochemistry, biotechnology, cell, drug development, enzymes, metabolism Books Book, Springer Science+Business Media

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Details zum Buch
Technological and Medical Implications of Metabolic Control Analysis
Autor:

Athel Cornish-Bowden

Titel:

Technological and Medical Implications of Metabolic Control Analysis

ISBN-Nummer:

The study of multienzyme systems has advanced considerably during the least decade. The cell is more complicated than classical biochemistry presents it, it contains more structure, and the behaviour of any system of enzymes is more elaborate than can be explained in simple terms. Nevertheless, classical enzymology and metabolism remain central to any modification of the metabolic behaviour of organisms, as attempted by modern biotechnology and drug development techniques. In this cool, objective look at the current state of the art, internationally respected authors draw attention to the drawbacks, problems, and opportunities associated with this exciting field. The areas covered include problems with current practice, the imposition of human objectives on organisms, understanding health and disease, computer modelling, the increasingly complex picture of cell structure, control and regulation of metabolism, and the general contribution metabolic control is making to biochemistry on a broader canvas.

Detailangaben zum Buch - Technological and Medical Implications of Metabolic Control Analysis


EAN (ISBN-13): 9780792361886
ISBN (ISBN-10): 0792361881
Gebundene Ausgabe
Erscheinungsjahr: 2000
Herausgeber: Springer-Verlag GmbH
392 Seiten
Gewicht: 0,748 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 02.04.2008 00:43:01
Buch zuletzt gefunden am 13.07.2017 13:23:15
ISBN/EAN: 9780792361886

ISBN - alternative Schreibweisen:
0-7923-6188-1, 978-0-7923-6188-6


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