2009, ISBN: 0470275006

[EAN: 9780470275009], Neubuch, [PU: WILEY Aug 2009], MEDICAL / NURSING; PHARMACOLOGY; PHARMACY, Besorgungstitel Neuware - Rare Book Procurement - Brings together functional and structural… Mehr…

[EAN: 9780470275009], Neubuch, [PU: WILEY Aug 2009], MEDICAL / NURSING; PHARMACOLOGY; PHARMACY, Besorgungstitel Neuware - Rare Book Procurement - Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymesThe second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets. Drug Design of Zinc-Enzyme Inhibitors brings together functional and structural information relevant to these zinc-containing targets. With up-to-date overviews of the latest developments field, this unique and comprehensive text enables readers to understand zinc enzymes and evaluate them in a drug design context.With contributions from the leaders of today's research, Drug Design of Zinc-Enzyme Inhibitors covers such key topics as:\\* Major drug targets like carbonic anhydrases, matrix metalloproteinases, bacterial proteases, angiotensin-converting enzyme, histone deacetylase, and APOBEC3G\\* Roles of recently discovered zinc-containing isozymes in cancer, obesity, epilepsy, pain management, malaria, and other conditions\\* Cross reactivity of zinc-enzyme inhibitors and activators\\* The extensive use of X-ray crystallography and QSAR studies for understanding zinc-containing proteins\\* Clinical applicationsAn essential resource for the discovery and development of new drug molecules, Drug Design of Zinc-Enzyme Inhibitors gives researchers, professionals, students, and academics the foundation to understand and work with zinc enzyme inhibitors and activators. 1056 pp. Eng, Books<

2009, ISBN: 0470275006

[EAN: 9780470275009], Neubuch, [PU: John Wiley & Sons], MEDICAL NURSING PHARMACOLOGY PHARMACY ARZNEIMITTELENTWICKLUNG CHEMIE CHEMISTRY DRUG DISCOVERY & DEVELOPMENT ENZYME U. REZEPTOREN EN… Mehr…

[EAN: 9780470275009], Neubuch, [PU: John Wiley & Sons], MEDICAL NURSING PHARMACOLOGY PHARMACY ARZNEIMITTELENTWICKLUNG CHEMIE CHEMISTRY DRUG DISCOVERY & DEVELOPMENT ENZYME U. REZEPTOREN ENZYMES RECEPTORS SCIENCE MEDIZIN PHARMACEUTICAL MEDICINE PHARMAKOLOGIE, Claudiu T. Supuran is a professor in the Department of Chemistry at the University of Florence, Italy. His main research interests include medicinal chemistry, design of enzyme inhibitors and activators, X-ray crystallography of metallo-enzymes, and metal c., Books<

ISBN: 9780470275009

Hardback, [PU: John Wiley & Sons Inc], The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and trans… Mehr…

Hardback, [PU: John Wiley & Sons Inc], The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the pharmaceutical industry., Pharmacology<

2009, ISBN: 9780470275009

Buch, Hardcover, [PU: John Wiley & Sons Inc], John Wiley & Sons Inc, 2009