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Interaction of Palmitic Acid with Metoprolol Succinate: at the Binding Sites of  Bovine Serum Albumin - Mohammad Firoz Khan, Jayanta Kishor chakrabarty, Mashiur Rahman
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Mohammad Firoz Khan, Jayanta Kishor chakrabarty, Mashiur Rahman:
Interaction of Palmitic Acid with Metoprolol Succinate: at the Binding Sites of Bovine Serum Albumin - Taschenbuch

2012, ISBN: 3659269549

Paperback, [EAN: 9783659269547], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], 2012-10-08, LAP LAMBERT Academic Publishing, The binding of Metoprolol succinate, a β-adrenoceptor blocker, to bovine serum albumin was studied by equilibrium dialysis method at 28˚C and pH 7.4. The study was carried out by using ranitidine and diazepam as site-I and site-II specific probe, respectively. Since, dietary fatty acids are highly protein bound, hence the binding profiles of metoprolol succinate were also characterized in presence or absence of Palmitic acid. The interactions of dietary fatty acids and other endogenous ligands are supposed to interfere the pharmacokinetics and protein binding profiles of the drugs. Therefore, the present study was undertaken to investigate the inside binding profiles of metoprolol sucinate and displacement of metoprolol sucinate from binding sites in presence of endogenous ligands or dietary components. This research provided the evidence of interaction of higher concentration of palmitic acid at the binding sites on BSA changing the pharmacokinetics properties of Metoprolol succinate. This in vitro research implies that high fat diet may enhance the free metoprolol concentration in blood which may ultimately alter the pharmacological and therapeutic actions of t, 265544, Pharmacology, 16311581, Cardiovascular, 16311631, Chemistry, 16311601, Clinical, 16311591, Drug Delivery Systems, 227673, Drug Guides, 227661, For Nurses, 227738, For Veterinarians, 16311541, Molecular, 16311571, Neuropsychopharmacology, 265547, Pain Medicine, 16311561, Pharmacodynamics, 265548, Pharmacy, 16311611, Product Development, 16311551, Reference, 265549, Toxicology, 173514, Medical Books, 1000, Subjects, 283155, Books

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Interaction of Palmitic Acid with Metoprolol Succinate: at the Binding Sites of Bovine Serum Albumin - Firoz Khan, Mohammad; Kishor chakrabarty, Jayanta; Rahman, Mashiur
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Firoz Khan, Mohammad; Kishor chakrabarty, Jayanta; Rahman, Mashiur:
Interaction of Palmitic Acid with Metoprolol Succinate: at the Binding Sites of Bovine Serum Albumin - Taschenbuch

2012, ISBN: 3659269549

ID: 13788490857

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Interaction of Palmitic Acid with Metoprolol Succinate: at the Binding Sites of Bovine Serum Albumin - Firoz Khan, Mohammad; Kishor chakrabarty, Jayanta; Rahman, Mashiur
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
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Firoz Khan, Mohammad; Kishor chakrabarty, Jayanta; Rahman, Mashiur:
Interaction of Palmitic Acid with Metoprolol Succinate: at the Binding Sites of Bovine Serum Albumin - Taschenbuch

2012, ISBN: 3659269549

ID: 13788490857

[EAN: 9783659269547], Neubuch, [PU: LAP LAMBERT Academic Publishing], This item is printed on demand for shipment within 3 working days.

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Interaction of Palmitic Acid with Metoprolol Succinate - Firoz Khan, Mohammad / Kishor chakrabarty, Jayanta / Rahman, Mashiur
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
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Firoz Khan, Mohammad / Kishor chakrabarty, Jayanta / Rahman, Mashiur:
Interaction of Palmitic Acid with Metoprolol Succinate - Taschenbuch

2012, ISBN: 3659269549

Gebundene Ausgabe, ID: 13105281

at the Binding Sites of Bovine Serum Albumin - Buch, gebundene Ausgabe, 96 S., Beilagen: Paperback, Erschienen: 2012 LAP Lambert Academic Publishing

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Interaction of Palmitic Acid with Metoprolol Succinate - Mohammad Firoz Khan
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Mohammad Firoz Khan:
Interaction of Palmitic Acid with Metoprolol Succinate - Taschenbuch

ISBN: 9783659269547

Paperback, [PU: LAP Lambert Academic Publishing]

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