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Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches - Biswajit Basu
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Biswajit Basu:
Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches - neues Buch

2012, ISBN: 9783659251115

[PU: LAP Lambert Academic Publishing], Das BuchFormulation And Evaluation Of Pimozide Buccal Mucoadhesive Patcheskönnte eine längere Lieferzeit habenSie zahlen eine Versandpauschale für bis zu fünf Bücher Typ:book Pimozide is an antipsychotic agent whose bioavailability is 4050 because of first pass metabolism The tmax of pimozide after oral administration is 412 hr which is long and variable Hence Pimozide is a suitable drug for buccal drug delivery log P of pimozide is 53432 Pimozide patches were prepared using HPMC (15 & 47 cps) carbopol 934 PVA and PVP FTIR and UV spectroscopic methods revealed no interaction between pimozide and polymers The patches were evaluated for their thickness uniformity folding endurance weight uniformity content uniformity swelling behaviour tensile strength and surface pH Data of in vitro release from patches were fit to different equations and kinetic models to explain release kinetics Kinetic models used were zero and firstorder equations HixonCrowell Higuchi and KorsmeyerPeppas models Good correlation among in vitro release and in vivo absorption of pimozide was observed Shortterm stability study revealed that drug content, DE, [SC: 0.00], Neuware, gewerbliches Angebot, 152, [GW: 633g], Skrill/Moneybookers, Banküberweisung, Interntationaler Versand

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Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches : Mucoadhesive Drug Delivery System - Biswajit Basu
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Biswajit Basu:
Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches : Mucoadhesive Drug Delivery System - Taschenbuch

2012, ISBN: 3659251119

ID: 22510440897

[EAN: 9783659251115], Neubuch, [PU: LAP Lambert Academic Publishing Sep 2012], This item is printed on demand - Print on Demand Neuware - Pimozide is an anti-psychotic agent whose bioavailability is 40-50% because of first pass metabolism. The tmax of pimozide after oral administration is 4-12 hr, which is long and variable. Hence, Pimozide is a suitable drug for buccal drug delivery. log P of pimozide is 5.3432. Pimozide patches were prepared using HPMC (15 & 47 cps), carbopol 934, PVA, and PVP. FTIR and UV spectroscopic methods revealed no interaction between pimozide and polymers. The patches were evaluated for their thickness uniformity, folding endurance, weight uniformity, content uniformity, swelling behaviour, tensile strength, and surface pH. Data of in vitro release from patches were fit to different equations and kinetic models to explain release kinetics. Kinetic models used were zero and first-order equations, Hixon-Crowell, Higuchi and Korsmeyer-Peppas models. Good correlation among in vitro release and in vivo absorption of pimozide was observed. Short-term stability study revealed that drug content decreased in various patches. 152 pp. Englisch

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Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches - Biswajit Basu
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Biswajit Basu:
Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches - Taschenbuch

2012, ISBN: 3659251119

ID: 22512077922

[EAN: 9783659251115], Neubuch, [PU: LAP Lambert Academic Publishing Sep 2012], Neuware - Pimozide is an anti-psychotic agent whose bioavailability is 40-50% because of first pass metabolism. The tmax of pimozide after oral administration is 4-12 hr, which is long and variable. Hence, Pimozide is a suitable drug for buccal drug delivery. log P of pimozide is 5.3432. Pimozide patches were prepared using HPMC (15 & 47 cps), carbopol 934, PVA, and PVP. FTIR and UV spectroscopic methods revealed no interaction between pimozide and polymers. The patches were evaluated for their thickness uniformity, folding endurance, weight uniformity, content uniformity, swelling behaviour, tensile strength, and surface pH. Data of in vitro release from patches were fit to different equations and kinetic models to explain release kinetics. Kinetic models used were zero and first-order equations, Hixon-Crowell, Higuchi and Korsmeyer-Peppas models. Good correlation among in vitro release and in vivo absorption of pimozide was observed. Short-term stability study revealed that drug content decreased in various patches. 152 pp. Englisch

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Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches - Biswajit Basu
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Biswajit Basu:
Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches - Taschenbuch

2012, ISBN: 3659251119

ID: 22512163973

[EAN: 9783659251115], Neubuch, [PU: LAP Lambert Academic Publishing Sep 2012], Neuware - Pimozide is an anti-psychotic agent whose bioavailability is 40-50% because of first pass metabolism. The tmax of pimozide after oral administration is 4-12 hr, which is long and variable. Hence, Pimozide is a suitable drug for buccal drug delivery. log P of pimozide is 5.3432. Pimozide patches were prepared using HPMC (15 & 47 cps), carbopol 934, PVA, and PVP. FTIR and UV spectroscopic methods revealed no interaction between pimozide and polymers. The patches were evaluated for their thickness uniformity, folding endurance, weight uniformity, content uniformity, swelling behaviour, tensile strength, and surface pH. Data of in vitro release from patches were fit to different equations and kinetic models to explain release kinetics. Kinetic models used were zero and first-order equations, Hixon-Crowell, Higuchi and Korsmeyer-Peppas models. Good correlation among in vitro release and in vivo absorption of pimozide was observed. Short-term stability study revealed that drug content decreased in various patches. 152 pp. Englisch

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Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches als Buch von Biswajit Basu - LAP Lambert Academic Publishing
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Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches als Buch von Biswajit Basu - neues Buch

ISBN: 9783659251115

ID: 820087660

Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches ab 59 EURO Mucoadhesive Drug Delivery System Formulation And Evaluation Of Pimozide Buccal Mucoadhesive Patches ab 59 EURO Mucoadhesive Drug Delivery System Bücher > Wissenschaft > Medizin

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EAN (ISBN-13): 9783659251115
ISBN (ISBN-10): 3659251119
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2012
Herausgeber: LAP Lambert Academic Publishing

Buch in der Datenbank seit 09.07.2009 19:58:54
Buch zuletzt gefunden am 11.08.2017 06:48:21
ISBN/EAN: 3659251119

ISBN - alternative Schreibweisen:
3-659-25111-9, 978-3-659-25111-5


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