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Stem cell and growth factor delivery vehicles for cartilage repair - Sukarto, Abby
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Sukarto, Abby:
Stem cell and growth factor delivery vehicles for cartilage repair - Taschenbuch

ISBN: 3659229814

ID: 22516036131

[EAN: 9783659229817], Neubuch, Publisher/Verlag: LAP Lambert Academic Publishing | Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair | Co-delivery of embedded growth factor-loaded microspheres and adult stem cells in a hydrogel matrix was studied for its potential as a cell-based therapeutic strategy for cartilage regeneration in partial thickness chondral defects. A photopolymerizable N-methacrylate glycol chitosan (MGC) was employed to form an in situ gel that was embedded with two formulations of growth factor-loaded microspheres and human adipose-derived stem cells (ASC). The polymeric microspheres were used as a delivery vehicle for the controlled release of growth factors to stimulate differentiation of the ASC towards the chondrocyte lineage. Bone morphogenetic protein-6 (BMP-6) and transforming growth factor-b3 (TGF-b3) were delivered at 5 ng/day at highly bioactive states. The ratio of collagen type II to I per cell was significantly higher for ASC chondrogenesis induced by the sustained release of BMP-6 and TGF-b3 in MGC gels than that of non-induced ASC or with soluble growth factor administration in the culture media. Thus, the co-delivery of growth factor-loaded microspheres and ASC in MGC gels successfully induced ASC chondrogenesis and is a promising strategy for cartilage repair. | Format: Paperback | Language/Sprache: english | 308 gr | 220x150x11 mm | 220 pp

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Stem cell and growth factor delivery vehicles for cartilage repair - Abby Sukarto
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Abby Sukarto:
Stem cell and growth factor delivery vehicles for cartilage repair - Taschenbuch

ISBN: 9783659229817

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], Neuware - Co-delivery of embedded growth factor-loaded microspheres and adult stem cells in a hydrogel matrix was studied for its potential as a cell-based therapeutic strategy for cartilage regeneration in partial thickness chondral defects. A photopolymerizable N-methacrylate glycol chitosan (MGC) was employed to form an in situ gel that was embedded with two formulations of growth factor-loaded microspheres and human adipose-derived stem cells (ASC). The polymeric microspheres were used as a delivery vehicle for the controlled release of growth factors to stimulate differentiation of the ASC towards the chondrocyte lineage. Bone morphogenetic protein-6 (BMP-6) and transforming growth factor-b3 (TGF-b3) were delivered at 5 ng/day at highly bioactive states. The ratio of collagen type II to I per cell was significantly higher for ASC chondrogenesis induced by the sustained release of BMP-6 and TGF-b3 in MGC gels than that of non-induced ASC or with soluble growth factor administration in the culture media. Thus, the co-delivery of growth factor-loaded microspheres and ASC in MGC gels successfully induced ASC chondrogenesis and is a promising strategy for cartilage repair., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 220x150x13 mm, 220, [GW: 344g], PayPal, offene Rechnung, Banküberweisung, sofortueberweisung.de, Interntationaler Versand

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Stem cell and growth factor delivery vehicles for cartilage repair als Buch von Abby Sukarto - Abby Sukarto
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Stem cell and growth factor delivery vehicles for cartilage repair:Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair Abby Sukarto Stem cell and growth factor delivery vehicles for cartilage repair:Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair Abby Sukarto Bücher > Wissenschaft > Medizin, LAP Lambert Academic Publishing

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ISBN: 9783659229817

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Stem cell and growth factor delivery vehicles for cartilage repair ab 79 EURO Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair Stem cell and growth factor delivery vehicles for cartilage repair ab 79 EURO Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair Bücher > Wissenschaft > Medizin

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Stem cell and growth factor delivery vehicles for cartilage repair: Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair - Sukarto, Abby
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
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Sukarto, Abby:
Stem cell and growth factor delivery vehicles for cartilage repair: Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair - Taschenbuch

2012, ISBN: 3659229814

ID: 21122411320

[EAN: 9783659229817], Neubuch, [PU: Lap Lambert Academic Publishing], This item is printed on demand for shipment within 3 working days.

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