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Possible New Screening Method for Anabolic Agents - Modification of Metabolic Pathways by Anabolic Agents and Identification of Gene Expression Biomarkers
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Possible New Screening Method for Anabolic Agents - Modification of Metabolic Pathways by Anabolic Agents and Identification of Gene Expression Biomarkers - Taschenbuch

2008, ISBN: 9783639080896

[ED: Taschenbuch / Paperback], [PU: VDM Verlag Dr. Müller], Anabolic androgenic substances (AAS) increase muscle mass, reduce total body fat and induce a positive nitrogen balance, resulting in higher performance. Therefore the use of AAS in competitive sports is of extreme attractivness but strictly illegal. In animal husbandry the application of AAS is legal in some countries but forbidden in the EU. Also in medical therapies anabolic agents are applied. The residue analysis methods for AAS are mostly based on confirmation of suspected samples via substance identification by mass spectrometry. It is also known that AAS can influence mRNA expression of specific genes. The aim of this thesis was to proof the possibility to detect AAS treatment via mRNA expression analysis. With the identification of biomarkers for anabolic agents using qRT-PCR, a gene expression pattern for AAS and metabolic pathways should be identified. First tissue specific biomarkers and effects on metabolic pathways could be detected. Theses biomarkers can be taken to establish a screening pattern for anabolic agents. Therefore, first steps toward a new screening method for anabolic agents could be done, helping to uncover abuses of anabolic agents in the future., [SC: 0.00], Neuware, gewerbliches Angebot, H: 220mm, B: 150mm, T: 4mm, [GW: 116g]

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Possible New Screening Method for Anabolic Agents - Reiter Martina
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Modification of Metabolic Pathways by Anabolic Agents and Identification of Gene Expression Biomarkers Anabolic androgenic substances (AAS) increase muscle mass, reduce total body fat and induce a positive nitrogen balance, resulting in higher performance. Therefore the use of AAS in competitive sports is of extreme attractivness but strictly illegal. In animal husbandry the application of AAS is legal in some countries but forbidden in the EU. Also in medical therapies anabolic agents are applied. The residue analysis methods for AAS are mostly based on confirmation of suspected samples via substance identification by mass spectrometry. It is also known that AAS can influence mRNA expression of specific genes. The aim of this thesis was to proof the possibility to detect AAS treatment via mRNA expression analysis. With the identification of biomarkers for anabolic agents using qRT-PCR, a gene expression pattern for AAS and metabolic pathways should be identified. First tissue specific biomarkers and effects on metabolic pathways could be detected. Theses biomarkers can be taken to establish a screening pattern for anabolic agents. Therefore, first steps toward a new screening method for anabolic agents could be done, helping to uncover abuses of anabolic agents in the future. Bücher / Fremdsprachige Bücher / Englische Bücher 978-3-639-08089-6, VDM

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Possible New Screening Method for Anabolic Agents - Reiter Martina
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ID: 117877586

Anabolic androgenic substances (AAS) increase muscle mass, reduce total body fat and induce a positive nitrogen balance, resulting in higher performance. Therefore the use of AAS in competitive sports is of extreme attractivness but strictly illegal. In animal husbandry the application of AAS is legal in some countries but forbidden in the EU. Also in medical therapies anabolic agents are applied. The residue analysis methods for AAS are mostly based on confirmation of suspected samples via substance identification by mass spectrometry. It is also known that AAS can influence mRNA expression of specific genes. The aim of this thesis was to proof the possibility to detect AAS treatment via mRNA expression analysis. With the identification of biomarkers for anabolic agents using qRT-PCR, a gene expression pattern for AAS and metabolic pathways should be identified. First tissue specific biomarkers and effects on metabolic pathways could be detected. Theses biomarkers can be taken to establish a screening pattern for anabolic agents. Therefore, first steps toward a new screening method for anabolic agents could be done, helping to uncover abuses of anabolic agents in the future. Modification of Metabolic Pathways by Anabolic Agents and Identification of Gene Expression Biomarkers Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, VDM

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Possible New Screening Method for Anabolic Agents - Martina Reiter
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2008, ISBN: 9783639080896

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Modification of Metabolic Pathways by Anabolic Agents and Identification of Gene Expression Biomarkers, unbekannt, Buch, [PU: VDM Verlag Dr. Müller]

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Anabolic androgenic substances (AAS) increase muscle, [PU: VDM Verlag Dr. Müller, Saarbrücken]

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Possible New Screening Method for Anabolic Agents
Autor:

Reiter Martina

Titel:

Possible New Screening Method for Anabolic Agents

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Anabolic androgenic substances (AAS) increase muscle mass, reduce total body fat and induce a positive nitrogen balance, resulting in higher performance. Therefore the use of AAS in competitive sports is of extreme attractivness but strictly illegal. In animal husbandry the application of AAS is legal in some countries but forbidden in the EU. Also in medical therapies anabolic agents are applied. The residue analysis methods for AAS are mostly based on confirmation of suspected samples via substance identification by mass spectrometry. It is also known that AAS can influence mRNA expression of specific genes. The aim of this thesis was to proof the possibility to detect AAS treatment via mRNA expression analysis. With the identification of biomarkers for anabolic agents using qRT-PCR, a gene expression pattern for AAS and metabolic pathways should be identified. First tissue specific biomarkers and effects on metabolic pathways could be detected. Theses biomarkers can be taken to establish a screening pattern for anabolic agents. Therefore, first steps toward a new screening method for anabolic agents could be done, helping to uncover abuses of anabolic agents in the future.

Detailangaben zum Buch - Possible New Screening Method for Anabolic Agents


EAN (ISBN-13): 9783639080896
ISBN (ISBN-10): 3639080890
Taschenbuch
Erscheinungsjahr: 2008
Herausgeber: VDM Verlag
76 Seiten
Gewicht: 0,130 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 25.09.2008 20:39:21
Buch zuletzt gefunden am 23.04.2017 11:49:45
ISBN/EAN: 3639080890

ISBN - alternative Schreibweisen:
3-639-08089-0, 978-3-639-08089-6


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