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Tumor Necrosis Factor
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Tumor Necrosis Factor - neues Buch

ISBN: 9781617374326

ID: 16549515

Tumor necrosis factor (TNF)-? is a pleiotropic cytokine involved in a va- ety of physiological and pathological processes. After initial discovery of its ability to induce cell death and animal cachexia, it was soon realized that this cytokine played pivotal roles in the regulation of homeostasis and inflam- tory-immune responses. This led to an explosion of interest in basic and tra- lational. Tumor necrosis factor (TNF)-? is a pleiotropic cytokine involved in a va- ety of physiological and pathological processes. After initial discovery of its ability to induce cell death and animal cachexia, it was soon realized that this cytokine played pivotal roles in the regulation of homeostasis and inflam- tory-immune responses. This led to an explosion of interest in basic and tra- lational research activities on the role of TNF in many diseases, such as cancer, septic shock, rheumatoid arthritis, and infectious diseases of the central n- vous system. Because of its potential therapeutic value, many academic and industrial research groups have worked to discover compounds that can block its activity. These studies have led to the approval of anti-TNF antibodies and soluble TNF receptors for the therapy of rheumatoid arthritis and Crohn's d- ease. TNF also can be an attractive anticancer agent capable of damaging tum- associated vessels and of inducing tumor necrosis in patients. The unique properties of TNF have led to its registration as a drug for locoregional tre- ment of sarcomas of the extremities, and stimulated many preclinical studies aimed at improving its therapeutic index for systemic USE. Tumor Necrosis Factor: Methods and Protocols provides an overview of basic and translational research along with a series of practical procedures on TNF production, characterization, mutagenesis, detection in biological spe- mens, as well as several in vitro assays and animal models for studying the role of TNF in various diseases. Books, Medical~~Clinical & Internal Medicine~~Diseases & Disorders, Tumor Necrosis Factor~~Book~~9781617374326, , , , , , , , , ,

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Tumor Necrosis Factor: Methods and Protocols - Herausgegeben von Corti, Angelo Ghezzi, Pietro
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Herausgegeben von Corti, Angelo Ghezzi, Pietro:
Tumor Necrosis Factor: Methods and Protocols - Taschenbuch

2010, ISBN: 9781617374326

[ED: Softcover], [PU: Springer, Berlin], Because tumor necrosis factor-a (TNF-a) plays a pivotal role in the regulation of homeostasis and inflammatory immune responses, it offers valuable research opportunities to develop new drugs for the treatment of a wide range of disorders, including cancer, septic shock, rheumatoid arthritis, and other inflammatory diseases. In Tumor Necrosis Factor: Methods and Protocols, well-versed experimentalists survey the basic and translational research being conducted in this field and describe in detail the methods they have developed for TNF production, characterization, mutagenesis, and detection in biological specimens. They also provide several in vitro assays and animal models for studying the role of TNF in various TNF-related diseases and in cancer. The protocols presented follow the successful Methods in Molecular Medicine(TM) series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and highly practical, Tumor Necrosis Factor: Methods and Protocols offers molecular and cellular biologists, pharmacologists, and toxicologists a diverse set of productive, cutting-edge tools for illuminating the pathophysiological roles of TNF in disease and for identifying new drugs. 2010. xii, 280 S. 63 SW-Abb.,. 229 mm Versandfertig in über 4 Wochen, [SC: 0.00], Neuware, gewerbliches Angebot

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Tumor Necrosis Factor  Methods and Protocols 1st Edition - Angelo Corti
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Tumor Necrosis Factor Methods and Protocols 1st Edition Author :Angelo Corti 9781617374326 1617374326

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Tumor Necrosis Factor - Angelo Corti; Pietro Ghezzi
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Angelo Corti; Pietro Ghezzi:
Tumor Necrosis Factor - Taschenbuch

2010, ISBN: 9781617374326

Gebundene Ausgabe, ID: 16168400

Softcover reprint of hardcover 1st ed. 2004, Softcover, Buch, [PU: Humana Press Inc.]

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Tumor Necrosis Factor - Angelo Corti; Pietro Ghezzi
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Angelo Corti; Pietro Ghezzi:
Tumor Necrosis Factor - Taschenbuch

2010, ISBN: 9781617374326

ID: 16168400

1st ed. Softcover of orig. ed. 2004, Softcover, Buch, [PU: Humana Press Inc.]

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Details zum Buch
Tumor Necrosis Factor: Methods and Protocols

A comprehensive collection of readily reproducible techniques for TNF production, characterization, mutagenesis, and detection in biological specimens. Also included are several in vitro assays and animal models for studying the role of TNF in various TNF-related diseases and in cancer. The collection offers molecular and cellular biologists, pharmacologists, and toxicologists a diverse set of versatile, cutting-edge tools for illuminating the pathophysiological roles of TNF in disease and for identifying new drugs.

Detailangaben zum Buch - Tumor Necrosis Factor: Methods and Protocols


EAN (ISBN-13): 9781617374326
ISBN (ISBN-10): 1617374326
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2010
Herausgeber: SPRINGER VERLAG GMBH
290 Seiten
Gewicht: 0,417 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 14.06.2011 15:50:41
Buch zuletzt gefunden am 14.11.2017 20:27:51
ISBN/EAN: 1617374326

ISBN - alternative Schreibweisen:
1-61737-432-6, 978-1-61737-432-6


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