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Platelet Glycoprotein Iib/iiia Inhibitors In Cardiovascular Disease
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ISBN: 9781617374081

One of the most important developments in the field of cardiovascular medicine over the last two decades has been recognition of the key role played by arterial thrombosis in the pathogenesis of acute coronary syndromes, ischemic complications of percutane- ous coronary revascularization, and coronary and peripheral atherosclerosis. The phar- macologic armamentarium directed against vascular thrombosis has thus expanded substantially during that time, with development of new fibrinolytic agents, low-molecu- lar-weight heparins, direct thrombin inhibitors, antagonists to platelet activation, and the platelet glycoprotein lIb/IlIa inhibitors. Though clinical investigations of these com- pounds have been marked by failures as well as successes, there is little doubt that enhanced antithrombotic therapies have markedly improved the outcome of patients undergoing coronary revascularization or with acute coronary syndromes. Glycoprotein IIblIlIa receptor antagonists were introduced into clinical practice to overcome the limitations of approaches that inhibit only individual pathways of platelet activation. Multiple mechanisms of platelet activation in response to different agonists converge on the platelet membrane glycoprotein IIblIlIa complex, the "final common pathway" of platelet aggregation. The clinical hemorrhagic syndrome caused by a rare inherited defect in this receptor (Glanzmann' s thrombasthenia), characterized by muco- cutaneous and postsurgical bleeding, but infrequent spontaneous organ (particularly central nervous system) bleeding, suggested that therapeutic inhibition of this receptor might be a potent, yet well-tolerated means of treating thrombotic disorders. Books Medical~~Clinical & Internal Medicine~~Cardiovascular Medicine Platelet Glycoprotein Iib/iiia Inhibitors In Cardiovascular Disease~~Book~~9781617374081 This substantially revised second edition contains new chapters on the role of GPIIb/IIIa blockade during acute coronary syndromes or with fibrinolytic therapy during acute myocardial infarctions, and updated and expanded information on the latest trials of GP IIb/IIIa inhibition during percutaneous coronary intervention. Additional improvements include a new chapter on outcomes with chronic oral GP IIb/IIIa blockade following acute coronary syndromes, discussion of GPIIb/IIIa blockade with other platelet and thrombin inhibitors, and a review of the potential effects beyond inhibition of platelet aggregation. Platelet Glycoprotein IIb/IIIa inhibitors in Cardiovascular Disease, Second Edition offers today's physicians, cardiologists, emergency room doctors, and basic scientists the most complete and authoritative review of the state-of-the-art in glycoprotein Iib/IIIa receptor inhibitor use.

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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease
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ISBN: 9781617374081

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This substantially revised second edition contains new chapters on the role of GPIIb/IIIa blockade during acute coronary syndromes or with fibrinolytic therapy during acute myocardial infarctions, and updated and expanded information on the latest trials of GP IIb/IIIa inhibition during percutaneous coronary intervention. Additional improvements include a new chapter on outcomes with chronic oral GP IIb/IIIa blockade following acute coronary syndromes, discussion of GPIIb/IIIa blockade with other platelet and thrombin inhibitors, and a review of the potential effects beyond inhibition of platelet aggregation. Platelet Glycoprotein IIb/IIIa inhibitors in Cardiovascular Disease, Second Edition offers today''s physicians, cardiologists, emergency room doctors, and basic scientists the most complete and authoritative review of the state-of-the-art in glycoprotein Iib/IIIa receptor inhibitor use. Books, Health and Well Being, Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease Books>Health and Well Being, Humana Press

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2003, ISBN: 9781617374081

ID: 694364122

Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease:Contemporary Cardiology. Softcover reprint of hardcover 2nd ed. 2003. Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease:Contemporary Cardiology. Softcover reprint of hardcover 2nd ed. 2003. Bücher > Wissenschaft > Medizin, Humana Press

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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease - A Michael Lincoff
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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease - Taschenbuch

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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease Platelet-Glycoprotein-IIb-IIIa-Inhibitors-in-Cardiovascular-Disease~~A-Michael-Lincoff Medicine>Medical Ref>Spec Procedure Paperback, Springer-Verlag New York, LLC

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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease - A. Michael Lincoff
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Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease - Taschenbuch

2010, ISBN: 9781617374081

ID: 16168381

2nd ed. Softcover of orig. ed. 2003, Softcover, Buch, [PU: Humana Press Inc.]

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Details zum Buch
Platelet Glycoprotein Iib/Iiia Inhibitors in Cardiovascular Disease

This substantially revised second edition contains new chapters on the role of GPIIb/IIIa blockade during acute coronary syndromes or with fibrinolytic therapy during acute myocardial infarctions, and updated and expanded information on the latest trials of GP IIb/IIIa inhibition during percutaneous coronary intervention. Additional improvements include a new chapter on outcomes with chronic oral GP IIb/IIIa blockade following acute coronary syndromes, discussion of GPIIb/IIIa blockade with other platelet and thrombin inhibitors, and a review of the potential effects beyond inhibition of platelet aggregation. Platelet Glycoprotein IIb/IIIa inhibitors in Cardiovascular Disease, Second Edition offers today's physicians, cardiologists, emergency room doctors, and basic scientists the most complete and authoritative review of the state-of-the-art in glycoprotein Iib/IIIa receptor inhibitor use.

Detailangaben zum Buch - Platelet Glycoprotein Iib/Iiia Inhibitors in Cardiovascular Disease


EAN (ISBN-13): 9781617374081
ISBN (ISBN-10): 1617374083
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2010
Herausgeber: SPRINGER VERLAG GMBH
440 Seiten
Gewicht: 0,816 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 29.11.2012 21:34:25
Buch zuletzt gefunden am 21.10.2017 20:04:35
ISBN/EAN: 1617374083

ISBN - alternative Schreibweisen:
1-61737-408-3, 978-1-61737-408-1


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