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Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - Denis Corbeil
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Denis Corbeil:
Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - neues Buch

11, ISBN: 9781461458944

ID: 203179781461458944

Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine. Oncology, Specialties, Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology~~ Denis Corbeil~~Oncology~~Specialties~~9781461458944, en, Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology, Denis Corbeil, 9781461458944, Springer, 11/19/2012, , , , Springer, 11/19/2012

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Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - Denis Corbeil
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Denis Corbeil:
Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - neues Buch

11, ISBN: 9781461458944

ID: 203179781461458944

Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine. Adult, Specialties, Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology~~ Denis Corbeil~~Adult~~Specialties~~9781461458944, en, Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology, Denis Corbeil, 9781461458944, Springer, 11/19/2012, , , , Springer, 11/19/2012

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Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - Denis Corbeil
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Denis Corbeil:
Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - neues Buch

2012, ISBN: 9781461458944

ID: 580309702

Since its first description fifteen years ago as a novel antigen of neural and hematopoietic stem cells, prominin-1 (alias CD133) has emerged concomitantly with stem and cancer stem cell research as an essential cell surface marker allowing identification and isolation of cells with stem cell properties. Although the physiological function of prominin-1 and the other members of prominin family remains elusive, its study has revealed new biological features regarding stem cells, cancer stem cells and photoreceptors. The latter cell type is illustrated by the association of mutations in prominin-1 (PROM1) gene with retinal degenerations including Stargardt-like macular dystrophy and retinitis pigmentosa. This book discusses these issues with contributions from leading experts in molecular and cellular biology, stem cells and tissue engineering. It also covers the potential role of prominin-1?positive stem cells in regenerative medicine, and its use as a biomarker of cancers originating from various organ systems and/or molecular target in cancer stem cell therapy. This book is an essential concise guide to the latest discoveries on prominin-1 and the applications in various medical research fields such as stem and cancer stem cells. Denis Corbeil holds a PhD in Biochemistry (University of Montreal, Canada). He is head of Tissue Engineering Laboratories, Biotechnological Centre (BIOTEC), Technische Universität Dresden, Dresden, Germany., 2012

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Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - Corbeil, Denis
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Corbeil, Denis:
Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - neues Buch

2012, ISBN: 1461458943

ID: 9781461458944

In englischer Sprache. Verlag: Springer New York, This book provides exciting new research on prominin-1/CD133. It evaluates this glycoprotein as a stem cell marker for cancers and other diseases and presents future prospects for its potential role in regenerative therapy. PC-PDF, 252 Seiten, XVI Seiten, 252 Seiten, [GR: 9692 - Nonbooks, PBS / Medizin/Nichtklinische Fächer], [SW: - Vorklinische Medizin, Grundlagenwissenschaften], [Ausgabe: 2013][PU:Springer New York]

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Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - Denis Corbeil;  Denis Corbeil
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Denis Corbeil; Denis Corbeil:
Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology - Erstausgabe

2012, ISBN: 9781461458944

ID: 26615675

[ED: 1], Auflage, eBook Download (PDF), eBooks, [PU: Springer-Verlag]

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Detailangaben zum Buch - Prominin-1 (CD133): New Insights on Stem Cancer Stem Cell Biology


EAN (ISBN-13): 9781461458944
ISBN (ISBN-10): 1461458943
Erscheinungsjahr: 2012
Herausgeber: Springer New York
250 Seiten
Sprache: eng/Englisch

Buch in der Datenbank seit 11.08.2012 07:36:24
Buch zuletzt gefunden am 11.02.2017 21:29:02
ISBN/EAN: 1461458943

ISBN - alternative Schreibweisen:
1-4614-5894-3, 978-1-4614-5894-4


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