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Metal and metalloid-containing compounds exhibit a wide range of biological and biocidal activities, some of which have been employed in medicines and drugs. Polymers containing metal or … Mehr…

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Biomedical Applications - gebrauchtes Buch

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Metal and metalloid-containing compounds exhibit a wide range of biological and biocidal activities, some of which have been employed in medicines and drugs. Polymers containing metal or … Mehr…

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Macromolecules Containing Metal and Metal?Like Elements: Biomedical Applications: v. 3 - Abd?El?Aziz, Alaa S. Carraher, Charles E. Pittman, Charles U. Sheats, John E. Zeldin, Martel
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2004

ISBN: 9780471667377

Wiley?Blackwell, Hardcover, Auflage: Volume 3, 218 Seiten, Publiziert: 2004-07-13T00:00:01Z, Produktgruppe: Book, 0.54 kg, General Medical Issues, Medical & Healthcare Practitioners, Heal… Mehr…

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2004, ISBN: 9780471667377

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John Wiley & Sons, Gebundene Ausgabe, Auflage: 1. Auflage, 218 Seiten, Publiziert: 2004-07-13T00:00:01Z, Produktgruppe: Buch, 1.19 kg, Medizin, Kategorien, Bücher, Chemie, Ingenieurwissen… Mehr…

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Macromolecules Containing Metal and Metal-Like Elements: Volume 3: Biomedical Applications - Erstausgabe

2004, ISBN: 9780471667377

Gebundene Ausgabe

John Wiley & Sons, Gebundene Ausgabe, Auflage: 1. Auflage, 218 Seiten, Publiziert: 2004-07-13T00:00:01Z, Produktgruppe: Buch, 1.19 kg, Medizin, Kategorien, Bücher, Chemie, Ingenieurwissen… Mehr…

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Bibliographische Daten des bestpassenden Buches

Details zum Buch
Macromolecules Containing Metal and Metal-Like Elements: Volume 3: Biomedical Applications

Metal and metalloid-containing compounds exhibit a wide range of biological and biocidal activities, some of which have been employed in medicines and drugs. Polymers containing metal or metalloid functions become a natural extension of this effort; just as organic compound drugs have been chemically bound to polymers or physically imbibed into polymer matrices in order to provide a variety of useful advantages, the same opportunities exist for using metal and metalloid species. This volume will cover important biomedical applications of organometallic compounds, including metal-labeled DNA on surfaces, artificial metallo-DNA, organotin molecules as anti-cancer drugs, and much more. * Provides useful descriptions of biomedical applications for the reader to apply in his/her research into materials, polymers, and medicine/drug development. * Edited by high-quality team of macromolecular experts from around the world

Detailangaben zum Buch - Macromolecules Containing Metal and Metal-Like Elements: Volume 3: Biomedical Applications


EAN (ISBN-13): 9780471667377
ISBN (ISBN-10): 0471667374
Gebundene Ausgabe
Erscheinungsjahr: 2004
Herausgeber: Abd-El-Aziz, Alaa S. Carraher, Charles E. Pittman, Charles U. Sheats, John E. Zeldin, Martel, John Wiley & Sons
218 Seiten
Gewicht: 0,531 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 2007-05-21T09:21:23+02:00 (Berlin)
Detailseite zuletzt geändert am 2023-06-22T12:22:39+02:00 (Berlin)
ISBN/EAN: 0471667374

ISBN - alternative Schreibweisen:
0-471-66737-4, 978-0-471-66737-7
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: charles martel, zeldin, abdelaziz, sheat, pittman, alaa
Titel des Buches: metal, metals, elements, macromolecules, con, biomedical applications, volume


Daten vom Verlag:

Autor/in: Alaa S. Abd-El-Aziz; Charles E. Carraher; Charles U. Pittman; John E. Sheats; Martel Zeldin
Titel: Macromolecules Containing Metal and Metal-like Elements; Macromolecules Containing Metal and Metal-Like Elements - Volume 3: Biomedical Applications
Verlag: John Wiley & Sons
Erscheinungsjahr: 2004-07-13
Gewicht: 0,510 kg
Sprache: Englisch
179,00 € (DE)
Not available (reason unspecified)

BB; GB; Hardcover, Softcover / Chemie/Organische Chemie; Organische Chemie; Polymere

Preface Series Preface 1. Organometallic Compounds in Biomedical Applications (Charles E. Carraher Jr. and Charles U. Pittman Jr.) I. Introduction II. Case for Metal-Containing Bioactive Agents A. Tin-Containing Biocidal Polymers B. Ferrocene: A Therapeutic Role in Polymeric Systems? C. Polymeric Moderation of OsO4 Toxicity III. Miscellaneous Polymers A. Metal Chelation Polymers B. Condensation Polymers IV. Small-Molecule Analogs V. Summary VI. References 2. Metal-Labeled DNA on Surfaces (Heinz-Bernhard Kraatz, Yitao Long, and Todd C. Sutherland) I. Introduction II. Ferrocene Nucleotides III. Ferrocene-DNA Conjugates IV. Other Metal-DNA Conjugates V. Metallated DNA A. Cu-DNA B. M-DNA VI. Summary VII. Acknowledgments VIII. References 3. Artificial DNA through Metal-Mediated Base Pairing: Structural Control and Discrete Metal Assembly (Mitsuhiko Shionoya) I. Introduction II. Alternative Hydrogen-Bonding Schemes for DNA Base Pairing III. Non-Hydrogen-Bonding Basepairs in DNA IV. Metal-Mediated Base Pairing in DNA A. Basic Concept B. Artificial Nucleosides Designed for Metal-Mediated Base Pairs C. Incorporation of a Metallo-Base Pair in DNA and Its Effect on Thermal Stability D. Discrete Self-Assembled Metal Arrays in DNA V. Future Prospects for Artificial Metallo-DNA VI. Summary VII. References 4. Organotin Macromolecules as Anticancer Drugs (Charles E. Carraher Jr. and Deborah Siegmann-Louda) I. General II. Anticancer Activity of Small Organotin Compounds III. Molecule-Level Studies on Monomeric Organotin Compounds IV. Anticancer Activity of Organotin Polymers V. Future Work VI. References 5. Organotin Oligomeric Drugs Containing the Antivirial Agent Acyclovir (Charles E. Carraher Jr. and Robert E. Bleicher) I. Early History of Organotin Compounds II. Mechanisms and Reactions III. General Structures IV. Acyclovir V. Bioactivity of Related Compounds VI. Experimental Work VII. Results and Discussion VIII. References 6. Polymeric Ferrocene Conjugates as Antiproliferative Agents (Eberhard W. Neuse) I. Introduction II. The Ferrocene-Ferricenium System in the Biological Environment III. Polymer-Drug Conjugation as a Pharmaceutical Tool for Drug Delivery IV. Polymer-Ferrocene Conjugates: Synthesis and Structure A. The Carrier Component: Structural Considerations B. Conjugates of Amide-Linked Ferrocene C. Conjugates of Ester-Linked Ferrocene V. Bioactivity Screening VI. Summary and Conclusions VII. Acknowledgments VIII.References 7. Polymeric Platinum-Containing Drugs in the Treatment of Cancer (Deborah W. Siegmann-Louda and Charles E. Carraher Jr) I. Introduction II. Basic Mechanisms of Pt(II) Complex Formation III. Nomenclature IV. Currently Approved Platinum-Containing Compounds V. Properties of Cisplatin VI. Structure-Activity Relationships VII. Polymer-Drug Conjugation Strategy and Possible Benefits A. Polymers as Carriers B. Polymers as Drugs C. General VIII. Mainchain-Incorporated cis-Diamine-Coordinated Platinum A. Simple Amine Derivatives B. Amino Acid Derivatives C. Other Nitrogen-Platinum Products D. Solution Stability E. Thermal Stability F. Antiviral Activity IX. Platinum Carrier-Bound Complexes via Nitrogen Donor Ligands A. Pt-Polyphosphazenes B. Slowly Biofissionable PtN Complexes Anchored through Primary and Secondary Amines C. Biofissionable PtN Complexes Anchored through Primary and Secondary Amines X. Pt-O-Bound Polymers XI. Mixed Pt-O/Pt-N-Bound Polymers XII. Future Work XIII. Acknowledgments XIV. References 8. New Organic Polyacid-Inorganic Compounds for Improved Dental Materials (Bill M. Culbertson, Minhhoa H. Dotrong, and Scott R. Schricker) I. Introduction II. Glass Ionomer Technology A. Amino Acid-Modified Glass Ionomers B. N-Vinylpyrrolidone (NVP)-Modified Glass Ionomers III. New NVP-Modified Glass Ionomers: Experimental Work A. Materials B. Polymer Synthesis C. Characterization D. Physical Properties IV. Results and Discussion V. Conclusions VI. References Index.

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