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2012, ISBN: 1461422175
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ISBN: 9781461422174
Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research fro… Mehr…
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Myelin Repair and Neuroprotection in Multiple Sclerosis | Robin J M Franklin (u. a.) | Buch | HC runder Rücken kaschiert | XIV | Englisch | 2012 | Springer US | EAN 9781461422174 - gebunden oder broschiert
2012
ISBN: 9781461422174
[ED: Gebunden], [PU: Springer US], Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclero… Mehr…
2012, ISBN: 1461422175
[EAN: 9781461422174], Neubuch, [PU: Springer], PRINT ON DEMAND Book; New; Fast Shipping from the UK., Books
ISBN: 9781461422174
Springer , pp. 304 . Hardback. New., Springer, 6
Bibliographische Daten des bestpassenden Buches
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Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier.
Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.
Detailangaben zum Buch - Myelin Repair and Neuroprotection in Multiple Sclerosis
EAN (ISBN-13): 9781461422174
ISBN (ISBN-10): 1461422175
Gebundene Ausgabe
Erscheinungsjahr: 20120831
Herausgeber: Springer-Verlag GmbH
287 Seiten
Gewicht: 0,593 kg
Sprache: Englisch
Buch in der Datenbank seit 2009-03-03T19:07:21+01:00 (Berlin)
Detailseite zuletzt geändert am 2023-12-05T10:53:28+01:00 (Berlin)
ISBN/EAN: 9781461422174
ISBN - alternative Schreibweisen:
1-4614-2217-5, 978-1-4614-2217-4
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: duncan, coetzee, frankl, franklin
Titel des Buches: repair sclerosis, multiple, franklin
Daten vom Verlag:
Autor/in: Ian D. Duncan; Robin J M Franklin
Titel: Myelin Repair and Neuroprotection in Multiple Sclerosis
Verlag: Springer; Springer US
290 Seiten
Erscheinungsjahr: 2012-08-31
New York; NY; US
Gedruckt / Hergestellt in Niederlande.
Sprache: Englisch
192,59 € (DE)
197,99 € (AT)
212,50 CHF (CH)
POD
XIV, 290 p.
BB; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Neurowissenschaften; Verstehen; Neuroscience; Neurology; Neuroradiology; Neurologie und klinische Neurophysiologie; Medizinische Bildverarbeitung: Radiologie; EA; BC
Development of oligodendrocytes in the vertebrate CNS.- Demyelination and remyelination in multiple sclerosis.- Microglia function in MS pathology.- Endogenous remyelination in the CNS.- Exogenous cell myelin repair and neuroprotection in multiple sclerosis.- A peripheral alternative to central nervous system myelin repair.- Immune modulation and repair following neural stem transplantation.- Axonal protection with sodium channel blocking agents in models of multiple sclerosis.- Effects of current medical therapies on reparative and neuroprotective functions in multiple sclerosis.- Imaging of demyelination and remyelination in multiple sclerosis.- Designing clinical trials to test neuroprotective therapies in multiple sclerosis..First book on this topic Authorship from many of the major players in the field of MS and myelin repair Of equal interest to academic clinical neurologists and neuroscientists Includes supplementary material: sn.pub/extras
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