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A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fa… Mehr…

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Metallointercalators : Synthesis and Techniques to Probe Their Interactions with Biomolecules - neues Buch

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A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fa… Mehr…

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Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules Janice Aldrich-Wright Editor
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Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules Janice Aldrich-Wright Editor - neues Buch

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2011, ISBN: 9783211990797

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Bibliographische Daten des bestpassenden Buches

Details zum Buch

Detailangaben zum Buch - Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules Janice Aldrich-Wright Editor


EAN (ISBN-13): 9783211990797
ISBN (ISBN-10): 3211990798
Erscheinungsjahr: 2011
Herausgeber: Springer Vienna Digital >16
427 Seiten
Sprache: eng/Englisch

Buch in der Datenbank seit 2011-08-22T21:33:31+02:00 (Berlin)
Detailseite zuletzt geändert am 2023-11-25T13:39:22+01:00 (Berlin)
ISBN/EAN: 3211990798

ISBN - alternative Schreibweisen:
3-211-99079-8, 978-3-211-99079-7
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: jan aldrich, janice, ald, will wright
Titel des Buches: probe


Daten vom Verlag:

Autor/in: Janice Aldrich-Wright
Titel: Metallointercalators - Synthesis and Techniques to Probe Their Interactions with Biomolecules
Verlag: Springer; Springer Wien
427 Seiten
Erscheinungsjahr: 2011-04-06
Vienna
Sprache: Englisch
149,79 € (DE)
149,79 € (AT)
177,00 CHF (CH)
Available
XXVIII, 427 p.

EA; E107; eBook; Nonbooks, PBS / Chemie/Anorganische Chemie; Anorganische Chemie; Verstehen; Biomolecular drug design; Inorganic Chemistry; Metallointercalator probe techniques; Metallointercalator synthesis; Metallointercalators; Physical Chemistry; B; Inorganic Chemistry; Pharmacy; Biochemistry; Physical Chemistry; Spectroscopy; Chemistry and Materials Science; Pharmazie, Apotheke; Biochemie; Physikalische Chemie; Spektroskopie, Spektrochemie, Massenspektrometrie; BB

A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery.

Introduction.- Synthesis:Platinum Intercalating Complexes; Binuclear Platinum Complexes;Binuclear Ruthenium and Platinum Intercalating Complexes; Sequence Selective Intercalating Complexes; Targeting and Improving Transport, Cucurbit[n]uril, Cylcodextrin and Dendrimers.- Techniques to Probe Interactions with Biomolecules:Introduction to NMR; DNA-NMR; PGSE-NMR; DNA ESI-MS; Investigating Binding Interactions using Linear Dichromism and Circular Dichromism; Flourescence Spectroscopy; Confocal Microscopy; Implementation of synchotron X-ray microscopy for investigations of the cellular uptake and cellular metabolism of metallointercalators; Biomolecular Helical Structure; Viscosity, TGA and Dialysis; Microarrays; Cytotoxicity-Cell lines; Antibacterical activity; Animal testing.

A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery.


Provides a detailed exposition on the propaedeutics and techniques illustrated with cogent examples Includes supplementary material: sn.pub/extras

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9783709116692 Metallointercalators (Herausgegeben:Aldrich-Wright, Janice)


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