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Cell surface proteoglycan signature of cancer cells and role of GPC-5 - Silvia Rossi
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ISBN: 9783838393919

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Glypicans, syndecans and NG2 in sarcoma cells and OSCC; role of glypican-5 in the control of cell motility in osteosarcoma cells Cell surface proteoglycans (PGs) play crucial regulatory roles in normal physiological processes and pathological conditions. The complexity of primary PG surface pattern (glypicans, syndecans and NG2) in tumour cells enables them to modulate several aspects of the tumour cell phenotype and the tumorigenic function of PGs is only in part resolved. We have focused our research on trying to understand how a given cell surface PG pattern may be involved in sarcomas and whether they could represent new potential prognostic/predictive markers in defined class of patients with OSCC. We have approached this problem defining the constitutive pattern of cell surface PGs expression in a large panel of sarcoma cells and OSCC biopsies and by creating 143B osteosarcoma cells de novo expressing GPC-5 assayed for its adhesion and migratory abilities in response to molecules of the extracellular matrix in vitro. The outcome of this project could provide the preliminary evidence that defined surface PGs pattern could differentially control cancer cells behavior and could be a new perspective in the understanding how these molecules regulate different aspects of cancer biology. Bücher / Fremdsprachige Bücher / Englische Bücher 978-3-8383-9391-9, LAP Lambert Academic Publishing

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Cell surface proteoglycan signature of cancer cells and role of GPC-5 - Silvia Rossi
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Silvia Rossi:

Cell surface proteoglycan signature of cancer cells and role of GPC-5 - neues Buch

ISBN: 9783838393919

ID: 471409048

Cell surface proteoglycans (PGs) play crucial regulatory roles in normal physiological processes and pathological conditions. The complexity of primary PG surface pattern (glypicans, syndecans and NG2) in tumour cells enables them to modulate several aspects of the tumour cell phenotype and the tumorigenic function of PGs is only in part resolved. We have focused our research on trying to understand how a given cell surface PG pattern may be involved in sarcomas and whether they could represent new potential prognostic/predictive markers in defined class of patients with OSCC. We have approached this problem defining the constitutive pattern of cell surface PGs expression in a large panel of sarcoma cells and OSCC biopsies and by creating 143B osteosarcoma cells de novo expressing GPC-5 assayed for its adhesion and migratory abilities in response to molecules of the extracellular matrix in vitro. The outcome of this project could provide the preliminary evidence that defined surface PGs pattern could differentially control cancer cells behavior and could be a new perspective in the understanding how these molecules regulate different aspects of cancer biology. Glypicans, syndecans and NG2 in sarcoma cells and OSCC; role of glypican-5 in the control of cell motility in osteosarcoma cells Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, LAP Lambert Academic Publishing

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Cell surface proteoglycan signature of cancer cells and role of GPC-5 - Silvia Rossi
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Cell surface proteoglycan signature of cancer cells and role of GPC-5 - neues Buch

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Cell surface proteoglycans (PGs) play crucial regulatory roles in normal physiological processes and pathological conditions. The complexity of primary PG surface pattern (glypicans, syndecans and NG2) in tumour cells enables them to modulate several aspects of the tumour cell phenotype and the tumorigenic function of PGs is only in part resolved. We have focused our research on trying to understand how a given cell surface PG pattern may be involved in sarcomas and whether they could represent new potential prognostic/predictive markers in defined class of patients with OSCC. We have approached this problem defining the constitutive pattern of cell surface PGs expression in a large panel of sarcoma cells and OSCC biopsies and by creating 143B osteosarcoma cells de novo expressing GPC-5 assayed for its adhesion and migratory abilities in response to molecules of the extracellular matrix in vitro. The outcome of this project could provide the preliminary evidence that defined surface PGs pattern could differentially control cancer cells behavior and could be a new perspective in the understanding how these molecules regulate different aspects of cancer biology. Bücher / Naturwissenschaften, Medizin, Informatik & Technik / Biologie

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Cell surface proteoglycan signature of cancer cells and role of GPC-5: Glypicans, syndecans and NG2 in sarcoma cells and OSCC; role of glypican-5 in the control of cell motility in osteosarcoma cells - Silvia Rossi
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Cell surface proteoglycan signature of cancer cells and role of GPC-5: Glypicans, syndecans and NG2 in sarcoma cells and OSCC; role of glypican-5 in the control of cell motility in osteosarcoma cells - Taschenbuch

ISBN: 3838393910

Taschenbuch, [EAN: 9783838393919], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], LAP LAMBERT Academic Publishing, 56488011, Biologie, 56458011, Biowissenschaften, 56047011, Fachbücher, 54071011, Genres, 52044011, Fremdsprachige Bücher

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Cell surface proteoglycan signature of cancer cells and role of GPC-5 - Rossi, Silvia
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Cell surface proteoglycan signature of cancer cells and role of GPC-5 - Taschenbuch

2010, ISBN: 3838393910

Gebundene Ausgabe, ID: 8725340

Glypicans, syndecans and NG2 in sarcoma cells and OSCC; role of glypican-5 in the control of cell motility in osteosarcoma cells - Buch, gebundene Ausgabe, 88 S., Beilagen: Paperback, Erschienen: 2010 LAP Lambert Acad. Publ.

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Cell surface proteoglycan signature of cancer cells and role of GPC-5
Autor:

Rossi, Silvia

Titel:

Cell surface proteoglycan signature of cancer cells and role of GPC-5

ISBN-Nummer:

9783838393919

Cell surface proteoglycans (PGs) play crucial regulatory roles in normal physiological processes and pathological conditions. The complexity of primary PG surface pattern (glypicans, syndecans and NG2) in tumour cells enables them to modulate several aspects of the tumour cell phenotype and the tumorigenic function of PGs is only in part resolved. We have focused our research on trying to understand how a given cell surface PG pattern may be involved in sarcomas and whether they could represent new potential prognostic/predictive markers in defined class of patients with OSCC. We have approached this problem defining the constitutive pattern of cell surface PGs expression in a large panel of sarcoma cells and OSCC biopsies and by creating 143B osteosarcoma cells de novo expressing GPC-5 assayed for its adhesion and migratory abilities in response to molecules of the extracellular matrix in vitro. The outcome of this project could provide the preliminary evidence that defined surface PGs pattern could differentially control cancer cells behavior and could be a new perspective in the understanding how these molecules regulate different aspects of cancer biology.

Detailangaben zum Buch - Cell surface proteoglycan signature of cancer cells and role of GPC-5


EAN (ISBN-13): 9783838393919
ISBN (ISBN-10): 3838393910
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2010
Herausgeber: LAP LAMBERT ACADEMIC PUB 01/10/2014

Buch in der Datenbank seit 23.08.2008 02:35:10
Buch zuletzt gefunden am 20.11.2016 06:44:09
ISBN/EAN: 9783838393919

ISBN - alternative Schreibweisen:
3-8383-9391-0, 978-3-8383-9391-9

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