Mechanisms in B-Cell Neoplasia 1990 : Workshop 1990 at the National Cancer Institute National Institutes of Health Bethesda, MD, USA, March 28¿30,1990 - Taschenbuch

EAN (ISBN-13): 9783642758911
ISBN (ISBN-10): 3642758916
Taschenbuch
Erscheinungsjahr: 2012
Herausgeber: Springer Berlin

Buch in der Datenbank seit 2012-08-23T21:12:07+02:00 (Berlin)
Detailseite zuletzt geändert am 2023-08-08T23:25:54+02:00 (Berlin)
ISBN/EAN: 9783642758911

ISBN - alternative Schreibweisen:
3-642-75891-6, 978-3-642-75891-1
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: fritz klein, pot, col melchers, fritz michael, potter potter potter, pott michael
Titel des Buches: the topic cancer, workshop mechanisms cell neoplasia, 1990, institut, bethesda

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Daten vom Verlag:

Autor/in: Michael Potter; Fritz Melchers
Titel: Current Topics in Microbiology and Immunology; Mechanisms in B-Cell Neoplasia 1990 - Workshop 1990 at the National Cancer Institute National Institutes of Health Bethesda, MD, USA, March 28–30,1990
Verlag: Springer; Springer Berlin
380 Seiten
Erscheinungsjahr: 2012-01-19
Berlin; Heidelberg; DE
Gedruckt / Hergestellt in Niederlande.
Sprache: Englisch
106,99 € (DE)
109,99 € (AT)
118,00 CHF (CH)
POD
XIX, 380 p.

BC; Hardcover, Softcover / Medizin/Klinische Fächer; Medizin: Allergien; Verstehen; Burkitt's Lymphoma; Lymphome; Myelome; Neoplasie; Onkologie; Tumoren; oncology; plasma cells; tumorigenesis; tumors; Allergology; Immunology; Oncology; Medical Microbiology; Virology; Immunologie; Onkologie; Mikrobiologie und Virologie; Mikrobiologie (nicht-medizinisch); BB; EA

IL-6 in Multiple Myeloma.- IL-6 as a Growth Factor for Human Multiple Myeloma Cells -A Short Overview.- Interleukin 6 (IL-6) and Its Receptor (IL-6R) in Myeloma/Plasmacytoma. With 7 Figures.- Interleukin-6 is a Major Myeloma Cell Growth Factor In Vitro and In Vivo Especially in Patients with Terminal Disease. With 4 Figures.- Macrophages as an Important Source of Paracrine IL6 in Myeloma Bone Marrow. With 1 Figure.- Retroviral-Mediated Transfer of Interleukin-6 Into Hematopoietic Cells of Mice Results in a Syndrome Resembling Castleman’s Disease. With 3 Figures.- A Monoclonal Antibody Specific for the Murine IL-6-Receptor Inhibits the Growth of a Mouse Plasmacytoma In Vivo. With 3 Figures.- Production of IL-2 in CD25 Positive Malignant Lymphomas.- IL-6 Induces Hybridoma Cell Growth Through a Novel Signalling Pathway. With 4 Figures.- Selective Killing of IL6 Receptor Bearing Myeloma Cells Using Recombinant IL6-Pseudomonas Toxin. With 2 Figures.- In Vitro Culture of a Primary Plasmacytoma that has Retained Its Dependence on Pristane Conditioned Microenvironment for Growth. With 1 Figure.- Experimental Plasmacytomas and B-Cell Tumors.- Modulation of Growth and Differentiation of Murine Myeloma Cells by Immunoglobulin Binding Factors. With 3 Figures.- A New Cell Adhesion Mechanism Involving Hyaluronate and CD44. With 1 Figure.- The Activity of an ABL-MYC Retrovirus in Fibroblast Cell Lines and in Lymphocytes. With 3 Figure.- Plasmacytoma Induction in BALB/c6;15 ? DBA/2 Chimeras.With 4 figures.- Mouse Plasmacytoma Associated (MPC) T(15;16) Translocation Occurs Repeatedly in New MPC Induction System. With 8 Figures.- A Retrovirus Expressing v-abl and c-myc Induces Plasmacytomas in 100% of Adult Pristane-PrimedBALB/c Mice. With 3 Figures.- Role of raf-1 Protein Kinase inIL-3 and GM-CSF-Mediated Signal Transduction.- Identification of Consensus Genes Expressed in Plasmacytomas but Not B Lymphomas. With 2 Figures.- Proliferation of B Cell Precursors in Bone Marrow of Pristane-Conditioned and Malaria-Infected Mice: Implications for B Cell Oncogenesis.- The Human CBLOncogene. With 5 Figures.- LymphoidTumorigenesis by v-abl and BCR-v-abl in Transgenic Mice. With 5 Figures.- Abnormalities of the Immune System Induced by Dysregulated bcl-2 Expression in Transgenic Mice. With 3 Figures.- Growth Regulation to B- Cells : Immortalization.- Immortalization of Primary Murine B Lymphocytes with Oncogene-ContainingRetroviral Vectors. With 2 Figures.- Functionality of Clonal Lymphoid Progenitor Cells Expressing the P210 BCR/ABL Oncogene. With 2 Figures.- Constitutive and Cell Cycle Regulated Expression of c-myc mRNA is Related to the State of Differentiation in Murine B-Lymphoid Tumors. With 3 Figures.- Bcl-2: B Cell Life, Death and Neoplasia.- C-myc Genes in B- Cell Neoplasia.- Binding of NF-KB-like Factors to Regulatory Sequences of the c-myc Gene. With 6 Figures.- Tumorigenesis in Transgenic Mice Expressing the c-mycOncogem with Various Lymphoid Enhancer Elements. With 8 Figures.- Isolation of Normal and Tumor-Specific Pvt-1 cDNA Clones. With 3 Figures.- Expression of c-myc and Pvt-1. With 4 Figures.- Mutational Analysis of the Carboxy-Terminal Casein Kinase II Phosphorylation Site in Human c-myc. With 2 Figures.- The Transforming Activity of PP59C-MYC is Weaker than that of v-myc. With 2 Figures.- Recombination of the c-myc Gene with IgH Enhancer-Sµ Sequences in a Murine Plasmacytoma (DCPC 21) Without Visible Chromosomal Translocations. With 9 Figures.- Downstream Regulatory Elements in the c-myc Gene. With 2 Figures.- DNA Repair in the c-mycLocus. With 2 Figures.- Mechanism of Negative Feed-back Regulation of c-myc Gene Expression in B-Cells and its Inactivation in Tumor Cells. With 5 Figures.- Moloney Murine Leukemia Virus Integration 1060 Base Pairs 5? of c-myc Exon 1 in a Plasmacytoma Without a Chromosomal Translocation. With 2 Figures.- Role of EBV in B-Cell Neoplasia.- Cell Phenotype Dependent Down-regulation of MHC Class I Antigens in Burkitt’s Lymphoma Cells. With 3 Figures.- EBV-Associated B-Cell Lymphomas Following Transfer of Human Peripheral Blood Lymphocytes to Mice with Severe Combined Immune Deficiency With 3 Figures.- Analysis of Epstein-Barr Virus Gene Expression in Lymphomas Derived from Normal Human B Cells Grafted into SCID Mice. With 4 Figures.- Deregulated c-mycGene Expression and Persistence of EBV are Not Sufficient to Maintain the Malignant Phenotype in Burkitt’s Lymphoma x B-Lymphoblastoid Hybrid Cells. With 2 Figures.- Epstein-Barr Virus Latency and Activation in Vivo. With 2 Figures.- Relative Predispositional Effect of a PADPRP Marker Allele in B-Cell and Some Non B-Cell Malignancies. With 4 Figures.- Epstein-Barr Virus Terminal Protein Gene Transcription is Dependent on EBNA 2 Expression and Provides Evidence for Viral Integration into the Host Genome. With 6 Figures.- Genomic Integration as a Novel Mechanism of EBV Persistence. With 2 Figures.- Effect of TGF-beta on the Proliferation of B Cell Lines and on the Immortalisation of B Cells by EBV.