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Current Concepts in Autoimmunity and Chronic Inflammation - A. Radbruch
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Current Concepts in Autoimmunity and Chronic Inflammation - neues Buch

2010, ISBN: 9783642067457

ID: 1001004011824324

The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principle of horror autotoxicus is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate ..., The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principle of horror autotoxicus is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate during immune cell ontogeny and subsequently on reactivity of mature lymphocytes in the periphery. They encompass mechanisms that are intrinsic to potentially reactive lymphocytes and can result in central or peripheral deletion or the alteration of functional potential. In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions. It is clear that the immune system devotes a considerable effort to the avoidance of the development of potentially pathogenic self-reactivity. Despite this, the development of self-reactivity is relatively common. - though the development of autoimmune disease is less frequent, autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, systemic lupus e- thematosus, psoriasis, thyroiditis, and myasthenia gravis, are all too common, and can cause considerable morbidity and even mortality.Taal: Engels; Afmetingen: 15x235x155 mm; Gewicht: 450,00 gram; Verschijningsdatum: februari 2010; ISBN10: 364206745X; ISBN13: 9783642067457; , Engelstalig | Paperback | 2010, School en studie, Exacte wetenschappen, Biologie, Studie & Management, Medisch & Gezondheid, Geneeskunde, Studie & Management, Exacte wetenschappen, Levenswetenschappen, School en studie, Exacte wetenschappen, Levenswetenschappen (biologie, biochemie & meer), School en studie, Geneeskunde, Meer geneeskunde, Springer

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Current Concepts in Autoimmunity and Chronic Inflammation - Herausgegeben von Radbruch, Andreas Lipsky, Peter E.
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Herausgegeben von Radbruch, Andreas Lipsky, Peter E.:

Current Concepts in Autoimmunity and Chronic Inflammation - Taschenbuch

2010, ISBN: 9783642067457

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[ED: Softcover], [PU: Springer, Berlin], The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principle of "horror autotoxicus" is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate during immune cell ontogeny and subsequently on reactivity of mature lymphocytes in the periphery. They encompass mechanisms that are intrinsic to potentially reactive lymphocytes and can result in central or peripheral deletion or the alteration of functional potential. In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions. It is clear that the immune system devotes a considerable effort to the avoidance of the development of potentially pathogenic self-reactivity. Despite this, the development of self-reactivity is relatively common. - though the development of autoimmune disease is less frequent, autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, systemic lupus e- thematosus, psoriasis, thyroiditis, and myasthenia gravis, are all too common, and can cause considerable morbidity and even mortality.Softcover reprint of hardcover 1st ed. 2006. 2010. ix, 282 S. 18 Tabellen. 235 mmVersandfertig in 3-5 Tagen, [SC: 0.00]

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Current Concepts in Autoimmunity and Chronic Inflammation - Andreas Radbruch, Peter E. Lipsky
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Andreas Radbruch, Peter E. Lipsky:
Current Concepts in Autoimmunity and Chronic Inflammation - Taschenbuch

ISBN: 364206745X

Paperback, [EAN: 9783642067457], Springer, Springer, Book, [PU: Springer], Springer, 948358, Immunology, 948348, Basic Sciences, 948300, Medical Books, 927726, Subjects, 916520, Books, 956812, Biological Sciences, 956832, Anatomy, 956574, Animals, 956836, Bacteriology, 956302, Biochemistry, 196545011, Bioelectricity, 956834, Bioinformatics, 956820, Biology, 956762, Biophysics, 51334011, Biorhythms, 956514, Biostatistics, 956814, Biotechnology, 956816, Botany, 16256061, Collection & Preservation, 956348, Ecology, 51335011, Ecotoxicology, 51336011, Fungi, 956366, Genetics, 51298011, Microscopy & Techniques, 956372, Paleontology, 956626, Plants, 51337011, Population Biology, 51338011, Research, 51339011, Taxonomic Classification, 956818, Zoology, 956280, Science & Math, 927726, Subjects, 916520, Books, 956926, Immunology, 956916, Basic Science, 956868, Medicine, 956280, Science & Math, 927726, Subjects, 916520, Books, 690430011, Immunology, 690424011, Basic Sciences, 690423011, Medicine, 15306671, Medicine, 15115321, Textbooks, 927726, Subjects, 916520, Books

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Current Concepts in Autoimmunity and Chronic Inflammation - Andreas Radbruch, Peter E. Lipsky
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Andreas Radbruch, Peter E. Lipsky:
Current Concepts in Autoimmunity and Chronic Inflammation - Taschenbuch

ISBN: 364206745X

Paperback, [EAN: 9783642067457], Springer, Springer, Book, [PU: Springer], Springer, 948358, Immunology, 948348, Basic Sciences, 948300, Medical Books, 927726, Subjects, 916520, Books, 956812, Biological Sciences, 956832, Anatomy, 956574, Animals, 956836, Bacteriology, 956302, Biochemistry, 196545011, Bioelectricity, 956834, Bioinformatics, 956820, Biology, 956762, Biophysics, 51334011, Biorhythms, 956514, Biostatistics, 956814, Biotechnology, 956816, Botany, 16256061, Collection & Preservation, 956348, Ecology, 51335011, Ecotoxicology, 51336011, Fungi, 956366, Genetics, 51298011, Microscopy & Techniques, 956372, Paleontology, 956626, Plants, 51337011, Population Biology, 51338011, Research, 51339011, Taxonomic Classification, 956818, Zoology, 956280, Science & Math, 927726, Subjects, 916520, Books, 956926, Immunology, 956916, Basic Science, 956868, Medicine, 956280, Science & Math, 927726, Subjects, 916520, Books, 690430011, Immunology, 690424011, Basic Sciences, 690423011, Medicine, 15306671, Medicine, 15115321, Textbooks, 927726, Subjects, 916520, Books

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Current Concepts in Autoimmunity and Chronic Inflammation - Andreas Radbruch; Peter E. Lipsky
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Andreas Radbruch; Peter E. Lipsky:
Current Concepts in Autoimmunity and Chronic Inflammation - Taschenbuch

2010, ISBN: 9783642067457

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Softcover reprint of hardcover 1st ed. 2006, Softcover, Buch, [PU: Springer Berlin]

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Current Concepts in Autoimmunity and Chronic Inflammation (Current Topics in Microbiology and Immunology)
Autor:

Andreas Radbruch, Peter E. Lipsky

Titel:

Current Concepts in Autoimmunity and Chronic Inflammation (Current Topics in Microbiology and Immunology)

ISBN-Nummer:

9783642067457

The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. However, clinical and experimental evidence suggests that the importance of an individual factor changes during the course of the disease. Factors and cell types that induce acute autoreactivity and initiate an autoimmune disease could be distinct from those that drive a chronic course of that disease.

Detailangaben zum Buch - Current Concepts in Autoimmunity and Chronic Inflammation (Current Topics in Microbiology and Immunology)


EAN (ISBN-13): 9783642067457
ISBN (ISBN-10): 364206745X
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2010
Herausgeber: Springer-Verlag GmbH
292 Seiten
Gewicht: 0,445 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 15.02.2012 14:34:44
Buch zuletzt gefunden am 15.11.2016 20:29:08
ISBN/EAN: 9783642067457

ISBN - alternative Schreibweisen:
3-642-06745-X, 978-3-642-06745-7

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