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Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry) - Jarkko Rautio, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
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Jarkko Rautio, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers:

Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry) - gebunden oder broschiert

ISBN: 3527326030

[SR: 2578740], Hardcover, [EAN: 9783527326037], Wiley VCH, Wiley VCH, Book, [PU: Wiley VCH], Wiley VCH, This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development., 270945, Pharmacology, 270906, Other Branches of Medicine, 270767, Medical & Healthcare Practitioners, 74, Health, Family & Lifestyle, 1025612, Subjects, 266239, Books, 278004, Chemistry, 278005, Analytical Chemistry, 277913, Biochemistry, 922214, Education, 922228, Geochemistry, 278012, Inorganic Chemistry, 278015, Laboratory Techniques & Experiments, 278016, Mineralogy, 278017, Organic Chemistry, 278020, Physical Chemistry, 922212, Reference, 57, Science & Nature, 1025612, Subjects, 266239, Books, 278202, Industrial Chemistry, 922268, Chemical, 278115, Engineering & Technology, 57, Science & Nature, 1025612, Subjects, 266239, Books, 564342, Chemistry, 564334, Scientific, Technical & Medical, 1025612, Subjects, 266239, Books

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Prodrugs and Targeted Delivery - Mannhold, Raimund; Kubinyi, Hugo; Folkers, Gerd; Rautio, Jarkko
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ISBN: 9783527326037

ID: 645017

By definition, drugs are highly active substances that are beneficial if they act at the right time and in the right place, but can cause harm otherwise. A clever strategy to ensure that a drug only becomes active when needed is to "camouflage" it. Such camouflaged, i.e. deactivated, drugs that become chemically or biochemically activated once they reach their site of action are called prodrugs. This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies, beginning at the early stages of the development process, while also discussing organ- and site-selective prodrugs. From the contents: * Prodrug design and intellectual property * Prodrugs addressing ADMET issues * Codrugs and soft drugs * Preclinical and clinical consideration for prodrugs This book is a valuable reference for all companies employing medicinal chemists by giving a practice-oriented overview of a key strategy in modern drug discovery and development. Technology Technology eBook, Wiley

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Prodrugs and Targeted Delivery - Jarkko Rautio
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ISBN: 9783527326037

[ED: Buch], [PU: Wiley VCH Verlag GmbH], Neuware - This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development. -, [SC: 0.00]

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Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry, Band 47) - Jarkko Rautio, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
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Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry, Band 47) - gebunden oder broschiert

ISBN: 3527326030

[SR: 1561437], Gebundene Ausgabe, [EAN: 9783527326037], Wiley-VCH Verlag GmbH & Co. KGaA, Wiley-VCH Verlag GmbH & Co. KGaA, Book, [PU: Wiley-VCH Verlag GmbH & Co. KGaA], Wiley-VCH Verlag GmbH & Co. KGaA, 56687011, Pharmakologie, 56690011, Pharmazie, 56689011, Schmerzmittel, 56691011, Toxikologie, 56535011, Medizin, 54071011, Genres, 52044011, Fremdsprachige Bücher

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Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry, Band 47) - Jarkko Rautio, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
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Jarkko Rautio, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers:
Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry, Band 47) - gebunden oder broschiert

ISBN: 3527326030

[SR: 1561437], Gebundene Ausgabe, [EAN: 9783527326037], Wiley-VCH Verlag GmbH & Co. KGaA, Wiley-VCH Verlag GmbH & Co. KGaA, Book, [PU: Wiley-VCH Verlag GmbH & Co. KGaA], Wiley-VCH Verlag GmbH & Co. KGaA, 56687011, Pharmakologie, 56690011, Pharmazie, 56689011, Schmerzmittel, 56691011, Toxikologie, 56535011, Medizin, 54071011, Genres, 52044011, Fremdsprachige Bücher

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Details zum Buch
Prodrugs and Targeted Delivery
Autor:

Jarkko Rautio

Titel:

Prodrugs and Targeted Delivery

ISBN-Nummer:

9783527326037

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.

Detailangaben zum Buch - Prodrugs and Targeted Delivery


EAN (ISBN-13): 9783527326037
ISBN (ISBN-10): 3527326030
Gebundene Ausgabe
Erscheinungsjahr: 2010
Herausgeber: Wiley VCH Verlag GmbH
496 Seiten
Gewicht: 1,104 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 16.01.2007 12:28:29
Buch zuletzt gefunden am 08.05.2016 16:57:17
ISBN/EAN: 9783527326037

ISBN - alternative Schreibweisen:
3-527-32603-0, 978-3-527-32603-7

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