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Integrins and Ion Channels - Molecular Complexes and Signaling - Becchetti, Andrea; Arcangeli, Annarosa
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Becchetti, Andrea; Arcangeli, Annarosa:

Integrins and Ion Channels - Molecular Complexes and Signaling - neues Buch

2010, ISBN: 144196066X

ID: 9781441960665

In englischer Sprache. Verlag: Springer New York, ANDREA BECCHETTI, PhD, is Professor of General, Comparative and Cellular Physiology at the Department of Biotechnology and Biosciences of the University of Milano-Bicocca, Italy. After receiving his academic degrees at the University of Milan, he has spent prolonged research sojourns at the Department of General Pathology of the University of Florence, Italy, the Department of Physiology at Emory University in Atlanta, Georgia, USA, the Department of Physiological Sciences of the University of Newcastle upon Tyne, UK, and the Biophysics Sector of the International School for Advanced Studies (ISAS-SISSA), in Trieste, Italy. His current research interests include the role of ion channels in cell adhesion and proliferation, the nicotinic modulation of synaptic transmission in the mammalian cerebral cortex and the pathogenesis of sleep-related epileptic forms linked to mutant human nicotinic receptors. Andrea Becchetti is member of the Society of General Physiologists, Biophysical Society, Society for Neuroscience and the Italian Physiological Society. ANNAROSA ARCANGELI, MD, PhD is Professor of General Pathology and Immunology at the Department of Experimental Pathology and Oncology of the University of Firenze (Florence, Italy). She is the Scientific Director of the Laboratory of Genetic Engineering for the Production of Animal Models of the University of Firenze. After receiving her MD degree at the University of Firenze, she spent several research sojourns at the Department of Physiology of the University of Milano, at the Institut d'Embriologie Cellulaire et Moleculaire, Nogent sur Marne, Paris, France and at the MRC-LMB Centre of Cambridge, UK. Her main research interests include the role of ion channels, in particular potassium channels, in the regulation of different aspects of tumor cell behaviour, including the cross talk with adhesion receptors, as well as the identification of ion channels as novel targets for cancer therapy. Annarosa Arcangeli is member of the Italian Society of Pathology, the Association of Cell Biology and Differentiation (ABCD), the American Society of Hematology. PC-PDF, 124 Seiten, XX Seiten, 124 Seiten, 1., st Edition. [GR: 9692 - Nonbooks, PBS / Medizin/Nichtklinische Fächer], [DRM: Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In other cases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel stimulation often controls integrin activation or expression. From a functional standpoint, studying the interplay between integrin receptors and ion channels clarifies how the extracellular matrix regulates processes as disparate as muscle excitability, synaptic plasticity and lymphocyte activation, just to mention a few. The derangement of these processes has many implications for pathogenesis processes, in particular for tumor invasiveness and some cardiovascular and neurologic diseases. This book provides a general introduction to the problems and methods of this blossoming field.], [Ausgabe: 1], [PU: Springer]

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Integrins and Ion Channels - Molecular Complexes and Signaling - Becchetti, Andrea; Arcangeli, Annarosa
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)

Becchetti, Andrea; Arcangeli, Annarosa:

Integrins and Ion Channels - Molecular Complexes and Signaling - neues Buch

2010, ISBN: 144196066X

ID: 9781441960665

In englischer Sprache. Verlag: Springer New York, ANDREA BECCHETTI, PhD, is Professor of General, Comparative and Cellular Physiology at the Department of Biotechnology and Biosciences of the University of Milano-Bicocca, Italy. After receiving his academic degrees at the University of Milan, he has spent prolonged research sojourns at the Department of General Pathology of the University of Florence, Italy, the Department of Physiology at Emory University in Atlanta, Georgia, USA, the Department of Physiological Sciences of the University of Newcastle upon Tyne, UK, and the Biophysics Sector of the International School for Advanced Studies (ISAS-SISSA), in Trieste, Italy. His current research interests include the role of ion channels in cell adhesion and proliferation, the nicotinic modulation of synaptic transmission in the mammalian cerebral cortex and the pathogenesis of sleep-related epileptic forms linked to mutant human nicotinic receptors. Andrea Becchetti is member of the Society of General Physiologists, Biophysical Society, Society for Neuroscience and the Italian Physiological Society. ANNAROSA ARCANGELI, MD, PhD is Professor of General Pathology and Immunology at the Department of Experimental Pathology and Oncology of the University of Firenze (Florence, Italy). She is the Scientific Director of the Laboratory of Genetic Engineering for the Production of Animal Models of the University of Firenze. After receiving her MD degree at the University of Firenze, she spent several research sojourns at the Department of Physiology of the University of Milano, at the Institut d'Embriologie Cellulaire et Moleculaire, Nogent sur Marne, Paris, France and at the MRC-LMB Centre of Cambridge, UK. Her main research interests include the role of ion channels, in particular potassium channels, in the regulation of different aspects of tumor cell behaviour, including the cross talk with adhesion receptors, as well as the identification of ion channels as novel targets for cancer therapy. Annarosa Arcangeli is member of the Italian Society of Pathology, the Association of Cell Biology and Differentiation (ABCD), the American Society of Hematology. PC-PDF, 124 Seiten, XX Seiten, 124 Seiten, 1., st Edition. [GR: 9692 - Nonbooks, PBS / Medizin/Nichtklinische Fächer], [SW: - Vorklinische Medizin, Grundlagenwissenschaften], [Ausgabe: 1], [PU: Springer]

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Integrins and Ion Channels - Molecular Complexes and Signaling - Becchetti, Andrea; Arcangeli, Annarosa
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Becchetti, Andrea; Arcangeli, Annarosa:
Integrins and Ion Channels - Molecular Complexes and Signaling - neues Buch

2010

ISBN: 144196066X

ID: 9781441960665

In englischer Sprache. Verlag: Springer New York, ANDREA BECCHETTI, PhD, is Professor of General, Comparative and Cellular Physiology at the Department of Biotechnology and Biosciences of the University of Milano-Bicocca, Italy. After receiving his academic degrees at the University of Milan, he has spent prolonged research sojourns at the Department of General Pathology of the University of Florence, Italy, the Department of Physiology at Emory University in Atlanta, Georgia, USA, the Department of Physiological Sciences of the University of Newcastle upon Tyne, UK, and the Biophysics Sector of the International School for Advanced Studies (ISAS-SISSA), in Trieste, Italy. His current research interests include the role of ion channels in cell adhesion and proliferation, the nicotinic modulation of synaptic transmission in the mammalian cerebral cortex and the pathogenesis of sleep-related epileptic forms linked to mutant human nicotinic receptors. Andrea Becchetti is member of the Society of General Physiologists, Biophysical Society, Society for Neuroscience and the Italian Physiological Society. ANNAROSA ARCANGELI, MD, PhD is Professor of General Pathology and Immunology at the Department of Experimental Pathology and Oncology of the University of Firenze (Florence, Italy). She is the Scientific Director of the Laboratory of Genetic Engineering for the Production of Animal Models of the University of Firenze. After receiving her MD degree at the University of Firenze, she spent several research sojourns at the Department of Physiology of the University of Milano, at the Institut d'Embriologie Cellulaire et Moleculaire, Nogent sur Marne, Paris, France and at the MRC-LMB Centre of Cambridge, UK. Her main research interests include the role of ion channels, in particular potassium channels, in the regulation of different aspects of tumor cell behaviour, including the cross talk with adhesion receptors, as well as the identification of ion channels as novel targets for cancer therapy. Annarosa Arcangeli is member of the Italian Society of Pathology, the Association of Cell Biology and Differentiation (ABCD), the American Society of Hematology. PC-PDF, 124 Seiten, XX Seiten, 124 Seiten, 1., st Edition. [GR: 9692 - Nonbooks, PBS / Medizin/Nichtklinische Fächer], [Ausgabe: 1], [PU: Springer]

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Integrins and Ion Channels - Molecular Complexes and Signaling - Becchetti, Andrea; Arcangeli, Annarosa
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Becchetti, Andrea; Arcangeli, Annarosa:
Integrins and Ion Channels - Molecular Complexes and Signaling - neues Buch

2010, ISBN: 144196066X

ID: 9781441960665

In englischer Sprache. Verlag: Springer New York, Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In othercases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel stimulation often controls integrin activation or expression. From a functional standpoint, studying the interplay between integrin receptors and ion channels clarifies how the extracellular matrix regulates processes as disparate as muscle excitability, synaptic plasticity and lymphocyte activation, just to mention a few. The derangement of these processes has many implications for pathogenesis processes, in particular for tumor invasiveness and some cardiovascular and neurologic diseases. This book provides a general introduction to the problems and methods of this blossoming field. PC-PDF, 20 Seiten, 20 Seiten, 1., st Edition. [GR: 9692 - Nonbooks, PBS / Medizin/Nichtklinische Fächer], [DRM: hard-drm], [Ausgabe: 1]

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Integrins and Ion Channels. - Molecular Complexes and Signaling - Andrea Becchetti, Annarosa Arcangeli
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Andrea Becchetti, Annarosa Arcangeli:
Integrins and Ion Channels. - Molecular Complexes and Signaling - neues Buch

ISBN: 9781441960665

ID: 232634

Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, integrins regulate many developmental processes in the widest sense (from cell choice between differentiation and proliferation, to tissue remodeling and organogenesis). Rapidly growing evidence shows that frequent communication takes place between cell adhesion receptors and channel proteins. This may occur through formation of multiprotein membrane complexes that regulate ion fluxes as well as a variety of intracellular signaling pathways. In other cases, cross talk is more indirect and mediated by cellular messengers such as G proteins. These interactions are reciprocal, in that ion channel stimulation often controls integrin activation or expression. From a functional standpoint, studying the interplay between integrin receptors and ion channels clarifies how the extracellular matrix regulates processes as disparate as muscle excitability, synaptic plasticity and lymphocyte activation, just to mention a few. The derangement of these processes has many implications for pathogenesis processes, in particular for tumor invasiveness and some cardiovascular and neurologic diseases. This book provides a general introduction to the problems and methods of this blossoming field., [PU: Springer]

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Integrins and Ion Channels.
Autor:

Andrea Becchetti;Annarosa Arcangeli

Titel:

Integrins and Ion Channels.

ISBN-Nummer:

9781441960665

Detailangaben zum Buch - Integrins and Ion Channels.


EAN (ISBN-13): 9781441960665
ISBN (ISBN-10): 144196066X
Erscheinungsjahr: 2010
Herausgeber: Springer New York
124 Seiten
Sprache: eng/Englisch

Buch in der Datenbank seit 22.05.2011 17:32:09
Buch zuletzt gefunden am 17.07.2014 18:17:48
ISBN/EAN: 9781441960665

ISBN - alternative Schreibweisen:
1-4419-6066-X, 978-1-4419-6066-5

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