Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed … Mehr…
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed at understanding molecular interactions and stability. Calorimeters have now become commonplace in bioscience laboratories. As a result, the number of those proficient in experimentation in this field has risen dramatically, as has the range of experiments to which these methods have been applied. Applications extend from studies in small molecule and solvent biophysics, through drug screening to whole cell assays. The technology has developed to include higher levels of sensitivity (and hence smaller sample size requirements) and a drive towards high-throughput technology, creating a very large user base in both academia and the pharmaceutical industry. This book is a fully revised and updated edition of the successful Biocalorimetry:Applications of Calorimetry in the Biological Sciences, published in 1998. Since then, there have been many advances in the instrumentation as well as in its applications and methodology. There are general chapters highlighting the usage of the isothermal titration calorimeter and the differential scanning calorimeter, more advanced chapters on specific applications and tutorials that cover the idiosyncrasies of experimental methods and data analysis. The book draws these together to create the definitive biological calorimetric text book. This book both explains the background to the method and describes novel, high-impact applications. It features works of interest to the experienced calorimetrist and the enthusiastic dilettante. The book should be of interest to all working in the field of biocalorimetry, from graduate students to researchers in academia and in industry.; PDF; Scientific, Technical and Medical > Biology, life sciences > Biochemistry, Wiley<
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Over the last decade, high-sensitivity calorimetry has developedfrom a specialist method used mainly by dedicated experts to amajor, commercially available tool in the arsenal directed at… Mehr…
Over the last decade, high-sensitivity calorimetry has developedfrom a specialist method used mainly by dedicated experts to amajor, commercially available tool in the arsenal directed atunderstanding molecular interactions and stability. Calorimetershave now become commonplace in bioscience laboratories. As aresult, the number of those proficient in experimentation in thisfield has risen dramatically, as has the range of experiments towhich these methods have been applied. Applications extend fromstudies in small molecule and solvent biophysics, through drugscreening to whole cell assays. The technology has developed toinclude higher levels of sensitivity (and hence smaller sample sizerequirements) and a drive towards high-throughput technology,creating a very large user base in both academia and thepharmaceutical industry. This book is a fully revised and updated edition of thesuccessful Biocalorimetry: Applications of Calorimetry inthe Biological Sciences, published in 1998. Since then, therehave been many advances in the instrumentation as well as in itsapplications and methodology. There are general chaptershighlighting the usage of the isothermal titration calorimeter andthe differential scanning calorimeter, more advanced chapters onspecific applications and tutorials that cover the idiosyncrasiesof experimental methods and data analysis. The book draws thesetogether to create the definitive biological calorimetric textbook. This book both explains the background to the method anddescribes novel, high-impact applications. It features worksof interest to the experienced calorimetrist and the enthusiasticdilettante. The book should be of interest to all working inthe field of biocalorimetry, from graduate students to researchersin academia and in industry. eBooks > Fremdsprachige eBooks > Englische eBooks > Sach- & Fachthemen > Biologie; eBooks > Fachbücher > Biowissenschaften , John Wiley & Sons Inc, John Wiley & Sons Inc<
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(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed … Mehr…
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed at understanding molecular interactions and stability. Calorimeters have now become commonplace in bioscience laboratories. As a result, the number of those proficient in experimentation in this field has risen dramatically, as has the range of experiments to which these methods have been applied. Applications extend from studies in small molecule and solvent biophysics, through drug screening to whole cell assays. The technology has developed to include higher levels of sensitivity (and hence smaller sample size requirements) and a drive towards high-throughput technology, creating a very large user base in both academia and the pharmaceutical industry. This book is a fully revised and updated edition of the successful Biocalorimetry:Applications of Calorimetry in the Biological Sciences, published in 1998. Since then, there have been many advances in the instrumentation as well as in its applications and methodology. There are general chapters highlighting the usage of the isothermal titration calorimeter and the differential scanning calorimeter, more advanced chapters on specific applications and tutorials that cover the idiosyncrasies of experimental methods and data analysis. The book draws these together to create the definitive biological calorimetric text book. This book both explains the background to the method and describes novel, high-impact applications. It features works of interest to the experienced calorimetrist and the enthusiastic dilettante. The book should be of interest to all working in the field of biocalorimetry, from graduate students to researchers in academia and in industry.; PDF; Scientific, Technical and Medical > Biology, life sciences, Wiley<
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No. 9780470011119. Versandkosten:Instock, Despatched same working day before 3pm, zzgl. Versandkosten. Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed … Mehr…
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed at understanding molecular interactions and stability. Calorimeters have now become commonplace in bioscience laboratories. As a result, the number of those proficient in experimentation in this field has risen dramatically, as has the range of experiments to which these methods have been applied. Applications extend from studies in small molecule and solvent biophysics, through drug screening to whole cell assays. The technology has developed to include higher levels of sensitivity (and hence smaller sample size requirements) and a drive towards high-throughput technology, creating a very large user base in both academia and the pharmaceutical industry. This book is a fully revised and updated edition of the successful Biocalorimetry:Applications of Calorimetry in the Biological Sciences, published in 1998. Since then, there have been many advances in the instrumentation as well as in its applications and methodology. There are general chapters highlighting the usage of the isothermal titration calorimeter and the differential scanning calorimeter, more advanced chapters on specific applications and tutorials that cover the idiosyncrasies of experimental methods and data analysis. The book draws these together to create the definitive biological calorimetric text book. This book both explains the background to the method and describes novel, high-impact applications. It features works of interest to the experienced calorimetrist and the enthusiastic dilettante. The book should be of interest to all working in the field of biocalorimetry, from graduate students to researchers in academia and in industry.; PDF; Scientific, Technical and Medical > Biology, life sciences > Biochemistry, Wiley<
No. 9780470011119. Versandkosten:Instock, Despatched same working day before 3pm, zzgl. Versandkosten.
Over the last decade, high-sensitivity calorimetry has developedfrom a specialist method used mainly by dedicated experts to amajor, commercially available tool in the arsenal directed at… Mehr…
Over the last decade, high-sensitivity calorimetry has developedfrom a specialist method used mainly by dedicated experts to amajor, commercially available tool in the arsenal directed atunderstanding molecular interactions and stability. Calorimetershave now become commonplace in bioscience laboratories. As aresult, the number of those proficient in experimentation in thisfield has risen dramatically, as has the range of experiments towhich these methods have been applied. Applications extend fromstudies in small molecule and solvent biophysics, through drugscreening to whole cell assays. The technology has developed toinclude higher levels of sensitivity (and hence smaller sample sizerequirements) and a drive towards high-throughput technology,creating a very large user base in both academia and thepharmaceutical industry. This book is a fully revised and updated edition of thesuccessful Biocalorimetry: Applications of Calorimetry inthe Biological Sciences, published in 1998. Since then, therehave been many advances in the instrumentation as well as in itsapplications and methodology. There are general chaptershighlighting the usage of the isothermal titration calorimeter andthe differential scanning calorimeter, more advanced chapters onspecific applications and tutorials that cover the idiosyncrasiesof experimental methods and data analysis. The book draws thesetogether to create the definitive biological calorimetric textbook. This book both explains the background to the method anddescribes novel, high-impact applications. It features worksof interest to the experienced calorimetrist and the enthusiasticdilettante. The book should be of interest to all working inthe field of biocalorimetry, from graduate students to researchersin academia and in industry. eBooks > Fremdsprachige eBooks > Englische eBooks > Sach- & Fachthemen > Biologie; eBooks > Fachbücher > Biowissenschaften , John Wiley & Sons Inc, John Wiley & Sons Inc<
Nr. A1031394260. Versandkosten:Lieferzeiten außerhalb der Schweiz 3 bis 21 Werktage, , Sofort per Download lieferbar, zzgl. Versandkosten. (EUR 17.05)
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed … Mehr…
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed at understanding molecular interactions and stability. Calorimeters have now become commonplace in bioscience laboratories. As a result, the number of those proficient in experimentation in this field has risen dramatically, as has the range of experiments to which these methods have been applied. Applications extend from studies in small molecule and solvent biophysics, through drug screening to whole cell assays. The technology has developed to include higher levels of sensitivity (and hence smaller sample size requirements) and a drive towards high-throughput technology, creating a very large user base in both academia and the pharmaceutical industry. This book is a fully revised and updated edition of the successful Biocalorimetry:Applications of Calorimetry in the Biological Sciences, published in 1998. Since then, there have been many advances in the instrumentation as well as in its applications and methodology. There are general chapters highlighting the usage of the isothermal titration calorimeter and the differential scanning calorimeter, more advanced chapters on specific applications and tutorials that cover the idiosyncrasies of experimental methods and data analysis. The book draws these together to create the definitive biological calorimetric text book. This book both explains the background to the method and describes novel, high-impact applications. It features works of interest to the experienced calorimetrist and the enthusiastic dilettante. The book should be of interest to all working in the field of biocalorimetry, from graduate students to researchers in academia and in industry.; PDF; Scientific, Technical and Medical > Biology, life sciences, Wiley<
No. 9780470011119. Versandkosten:Instock, Despatched same working day before 3pm, zzgl. Versandkosten.
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Buch in der Datenbank seit 2007-02-02T06:35:29+01:00 (Berlin) Detailseite zuletzt geändert am 2023-11-23T21:20:30+01:00 (Berlin) ISBN/EAN: 9780470011119
ISBN - alternative Schreibweisen: 0-470-01111-4, 978-0-470-01111-9 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: john doyle, berger
Daten vom Verlag:
Autor/in: John E. Ladbury; Michael L. Doyle Titel: Biocalorimetry 2 - Applications of Calorimetry in the Biological Sciences Verlag: Wiley; John Wiley & Sons 276 Seiten Erscheinungsjahr: 2005-07-15 Sprache: Englisch 141,99 € (DE) Not available (reason unspecified)
EA; E107; E-Book; Nonbooks, PBS / Biologie/Mikrobiologie; Biologie, Biowissenschaften; Biochemie; Biotechnologie i. d. Biowissenschaften; Biotechnology; Biowissenschaften; Cell & Molecular Biology; Life Sciences; Molekularbiologie; Zell- u. Molekularbiologie; Zell- u. Molekularbiologie; Biotechnologie i. d. Biowissenschaften; BB
Preface. List of Contributors. PART I: GENERAL INTRODUCTION. 1. Applications of Biocalorimetry: Binding, Stability and EnzymeKinetics (R. O'Brien and I. Haq). PART II: ISOTHERMAL TITRATION CALORIMETRY. 2. Isothermal Titration Calorimetry: A Tutorial (J.A. Thomsonand J.E. Ladbury). 3. The Application of Isothermal Titration Calorimetry to DrugDiscovery (G. Holdgate. S. Fisher and W. Ward). 4. Dissecting the Thermodynamics of DNA-Protein Interactions (T.Härd). 5. Salt Effects in Ribonuclease-Ligand Interactions: Screeningor Competitive Binding? (K.P. Murphy, T.T. Waldron and G.L.Schrift) 6. Thermodynamic-Structure Correlations of Sulfonamide InhibitorBinding to Carbonic Anhydrase (D. Matulis and M. Todd). 7. Energetics of the Interaction of Human Acidic FibroblastGrowth Factor with Heparin and the Functional AnalogMyo-inositol Hexasulfate (M. Guzmán-Casado, M.M.Garcia-Mira, P. Cano-Soldado, J.M. Sanchez-Ruiz and A.Parody-Morreale). 8. Thermodynamics of SH2 Domain Binding (G. Waksman, S. Kumaranand P. Lubman). 9. Titration Calorimetry as a Tool to Determining Thermodyanmicand Kinetic Parameters of Enzymes (M.L. Bianconi). PART III: DIFFERENTIAL SCANNING CALORIMETRY. 10. Energetics of Site-Specific DNA Recognition by IntegraseTn916 (S. Milev, H.R. Bosshard and I. Jelesarov). 11. Linkage Between Temperature and Chemical Denaturant Effectson Protein Stability: The Intepretation ofCalorimetrically-Determined m Values (B. Ibarra-Malero,R. Perez-Jimenez, R. Godoy-Ruiz and J.M. Sanchez-Ruiz). 12. Thermodymic Indications of the Molten Globule State ofCytochrome c Induced by Hydrophobic Salts (A.A.Moosavi-Movahedi and J. Chamani). 13. Microcalorimetry as Applied to Psychrophilic Enzymes (S.D'Amico, D. Georlette, T. Collins, G. Feller and C.Gerday). 14. An Autosampling Differential Scanning Calorimeter for Studyof Biomolecular Interactions (V. Plotnikov, A. Rochalski, M.Brandts, J.F. Brandts, S. Williston, V. Frasca and L.-N. Lin). Index.
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