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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid: Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids - Barun Majumder
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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid: Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids - Taschenbuch

ISBN: 3845409185

Paperback, [EAN: 9783845409184], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], LAP LAMBERT Academic Publishing, Dietary Eicosapentaenoic Acid (EPA), Conjugated Linoleic Acid (CLA) and Oleic Acid (OA) have been postulated to reduce the risk of breast cancer. This study has examined the effects of these dietary fatty acids on the induction of apoptosis in normal breast epithelial (MCF-10A), oestrogen receptor positive (MCF-7) and oestrogen receptor negative breast cancer cells (MDA-MB-231).Cell proliferation was assessed using the MTT assay, and the comet assay was used to examine the extent of DNA damage (as a marker of apoptosis). Changes in the expression of mRNA and the proteins of the major pro-apoptotic P53, p21WAF1/CIP1, BAX, BCL-XS genes and the anti-apoptotic BCL-2 gene were determined in these cell lines in vitro. The greatest cell growth inhibition and induction of apoptosis was observed after exposure to CLA. Further investigations focussed on the mechanisms underlying the anti-tumour effects of CLA. CLA increased P53 and p21WAF1/CIP1 mRNA expression (3-5-fold and 2-fold respectively) and decreased BCL-2 by 20-30%. Protein expression reflected the changes in mRNA expression., 4673, Breast Cancer, 171141, Cancer, 4656, Diseases & Physical Ailments, 10, Health, Fitness & Dieting, 1000, Subjects, 283155, Books, 173514, Medical Books, 227560, Administration & Medicine Economics, 227571, Allied Health Professions, 227191, Basic Sciences, 227604, Dentistry, 3559244011, History, 266181, Medical Informatics, 265542, Medicine, 227640, Nursing, 265544, Pharmacology, 6511980011, Psychology, 227677, Research, 227719, Veterinary Medicine, 1000, Subjects, 283155, Books, 689783011, General, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books

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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - Barun Majumder
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ISBN: 9783845409184

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Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids Dietary Eicosapentaenoic Acid (EPA), Conjugated Linoleic Acid (CLA) and Oleic Acid (OA) have been postulated to reduce the risk of breast cancer. This study has examined the effects of these dietary fatty acids on the induction of apoptosis in normal breast epithelial (MCF-10A), oestrogen receptor positive (MCF-7) and oestrogen receptor negative breast cancer cells (MDA-MB-231).Cell proliferation was assessed using the MTT assay, and the comet assay was used to examine the extent of DNA damage (as a marker of apoptosis). Changes in the expression of mRNA and the proteins of the major pro-apoptotic P53, p21WAF1/CIP1, BAX, BCL-XS genes and the anti-apoptotic BCL-2 gene were determined in these cell lines in vitro. The greatest cell growth inhibition and induction of apoptosis was observed after exposure to CLA. Further investigations focussed on the mechanisms underlying the anti-tumour effects of CLA. CLA increased P53 and p21WAF1/CIP1 mRNA expression (3-5-fold and 2-fold respectively) and decreased BCL-2 by 20-30%. Protein expression reflected the changes in mRNA expression. Bücher / Fremdsprachige Bücher / Englische Bücher 978-3-8454-0918-4, LAP Lambert Academic Publishing

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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - Barun Majumder
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Barun Majumder:
Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - Taschenbuch

ISBN: 3845409185

Paperback, [EAN: 9783845409184], LAP Lambert Academic Publishing, LAP Lambert Academic Publishing, Book, [PU: LAP Lambert Academic Publishing], LAP Lambert Academic Publishing, 270767, Medical & Healthcare Practitioners, 270768, Ancillary Services, 270792, Basic Medical Science, 276871, Encyclopaedias, 270842, Internal Medicine, 270893, Nursing, 270906, Other Branches of Medicine, 270952, Surgery, 74, Health, Family & Lifestyle, 1025612, Subjects, 266239, Books, 922532, Medicine, 270792, Basic Science, 922534, Dentistry, 922610, Diseases & Disorders, 922810, Education, 922556, Hospital Administration & Management, 922558, Medical Ethics & Legal Issues, 922560, Medical Research & Equipment, 922572, Medical Sciences A-Z, 270781, Midwifery, 922778, Nursing, 922802, Optometry, 922804, Pharmacy, 922806, Physiotherapy, 922808, Reference, 57, Science & Nature, 1025612, Subjects, 266239, Books, 564356, Medicine & Nursing, 270792, Basic Medical Science, 13393701, Exams, 13393791, Study & Revision Guides, 571382, Medical Sciences A-Z, 270915, Dentistry, 571476, Midwifery, 571456, Nursing, 573568, Pharmacy, 573564, Physiotherapy, 571478, First Aid & Paramedical Services, 571280, Medical Research & Equipment, 573664, Reference, 564334, Scientific, Technical & Medical, 1025612, Subjects, 266239, Books

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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - Barun Majumder
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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - neues Buch

ISBN: 9783845409184

ID: d72c5a7bbf05bb6fa48f41286113e837

Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids Dietary Eicosapentaenoic Acid (EPA), Conjugated Linoleic Acid (CLA) and Oleic Acid (OA) have been postulated to reduce the risk of breast cancer. This study has examined the effects of these dietary fatty acids on the induction of apoptosis in normal breast epithelial (MCF-10A), oestrogen receptor positive (MCF-7) and oestrogen receptor negative breast cancer cells (MDA-MB-231).Cell proliferation was assessed using the MTT assay, and the comet assay was used to examine the extent of DNA damage (as a marker of apoptosis). Changes in the expression of mRNA and the proteins of the major pro-apoptotic P53, p21WAF1/CIP1, BAX, BCL-XS genes and the anti-apoptotic BCL-2 gene were determined in these cell lines in vitro. The greatest cell growth inhibition and induction of apoptosis was observed after exposure to CLA. Further investigations focussed on the mechanisms underlying the anti-tumour effects of CLA. CLA increased P53 and p21WAF1/CIP1 mRNA expression (3-5-fold and 2-fold respectively) and decreased BCL-2 by 20-30%. Protein expression reflected the changes in mRNA expression. Bücher / Fremdsprachige Bücher / Englische Bücher 978-3-8454-0918-4, LAP Lambert Acad. Publ.

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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - Barun Majumder
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Barun Majumder:
Modulation of Breast Cancer Genes by Conjugated Linoleic Acid - neues Buch

ISBN: 9783845409184

ID: 155453925

Dietary Eicosapentaenoic Acid (EPA), Conjugated Linoleic Acid (CLA) and Oleic Acid (OA) have been postulated to reduce the risk of breast cancer. This study has examined the effects of these dietary fatty acids on the induction of apoptosis in normal breast epithelial (MCF-10A), oestrogen receptor positive (MCF-7) and oestrogen receptor negative breast cancer cells (MDA-MB-231).Cell proliferation was assessed using the MTT assay, and the comet assay was used to examine the extent of DNA damage (as a marker of apoptosis). Changes in the expression of mRNA and the proteins of the major pro-apoptotic P53, p21WAF1/CIP1, BAX, BCL-XS genes and the anti-apoptotic BCL-2 gene were determined in these cell lines in vitro. The greatest cell growth inhibition and induction of apoptosis was observed after exposure to CLA. Further investigations focussed on the mechanisms underlying the anti-tumour effects of CLA. CLA increased P53 and p21WAF1/CIP1 mRNA expression (3-5-fold and 2-fold respectively) and decreased BCL-2 by 20-30%. Protein expression reflected the changes in mRNA expression. Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher

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Modulation of Breast Cancer Genes by Conjugated Linoleic Acid: Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids
Autor:

Majumder, Barun

Titel:

Modulation of Breast Cancer Genes by Conjugated Linoleic Acid: Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids

ISBN-Nummer:

3845409185

Detailangaben zum Buch - Modulation of Breast Cancer Genes by Conjugated Linoleic Acid: Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids


EAN (ISBN-13): 9783845409184
ISBN (ISBN-10): 3845409185
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2011
Herausgeber: LAP Lambert Acad. Publ. Aug 2011

Buch in der Datenbank seit 08.12.2008 11:10:44
Buch zuletzt gefunden am 18.09.2016 03:08:31
ISBN/EAN: 3845409185

ISBN - alternative Schreibweisen:
3-8454-0918-5, 978-3-8454-0918-4

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