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Kleinster Preis: 49.00 EUR, größter Preis: 102.42 EUR, Mittelwert: 59.68 EUR
Gene Therapy for Breast Cancer Treatment - Laura Vannucci
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Laura Vannucci:

Gene Therapy for Breast Cancer Treatment - Taschenbuch

ISBN: 9783844322071

ID: 597774386

LAP Lambert Academic Publishing. Paperback. New. Paperback. 80 pages. Dimensions: 8.7in. x 5.9in. x 0.2in.Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN., LAP Lambert Academic Publishing

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Gene therapy for breast cancer treatment - Laura Vannucci
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Gene therapy for breast cancer treatment - neues Buch

ISBN: 9783844322071

ID: 3e6ace80082db679c783224d02f964ae

Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. Buch / Broschur

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Gene therapy for breast cancer treatment - Vannucci, Laura
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Vannucci, Laura:
Gene therapy for breast cancer treatment - Taschenbuch

2011

ISBN: 3844322078

Gebundene Ausgabe, ID: 10422235

Engineered viruses: to turn the bad into the good - Buch, gebundene Ausgabe, 80 S., Beilagen: Paperback, Erschienen: 2011 LAP Lambert Acad. Publ.

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Gene therapy for breast cancer treatment - Laura Vannucci
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Laura Vannucci:
Gene therapy for breast cancer treatment - neues Buch

2011, ISBN: 9783844322071

ID: 18850848

Engineered viruses: to turn the bad into the good, unbekannt, Buch, [PU: LAP Lambert Academic Publishing]

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Gene therapy for breast cancer treatment - Laura Vannucci
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Laura Vannucci:
Gene therapy for breast cancer treatment - neues Buch

2011, ISBN: 9783844322071

ID: 18850848

Engineered viruses: to turn the bad into the good, unbekannt, Buch, [PU: LAP Lambert Academic Publishing]

Neues Buch Lehmanns.de
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Gene therapy for breast cancer treatment
Autor:

Vannucci, Laura

Titel:

Gene therapy for breast cancer treatment

ISBN-Nummer:

3844322078

Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer.

Detailangaben zum Buch - Gene therapy for breast cancer treatment


EAN (ISBN-13): 9783844322071
ISBN (ISBN-10): 3844322078
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2011
Herausgeber: LAP Lambert Academic Publishing

Buch in der Datenbank seit 26.09.2007 21:46:40
Buch zuletzt gefunden am 07.10.2015 20:23:12
ISBN/EAN: 3844322078

ISBN - alternative Schreibweisen:
3-8443-2207-8, 978-3-8443-2207-1

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