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Kleinster Preis: 16.04 EUR, größter Preis: 325.70 EUR, Mittelwert: 162.98 EUR
Pathogenesis of Neurodegenerative Disorders - Mark P. Mattson (Editor)
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Mark P. Mattson (Editor):

Pathogenesis of Neurodegenerative Disorders - gebrauchtes Buch

ISBN: 9780896038387

ID: 9780896038387

Recent scientific advances have dramatically expanded our understanding of the molecular, genetic, and environmental factors that either cause or contribute to a wide variety of age-related neurodegenerative disorders. In Pathogenesis of Neurodegenerative Disorders, leading experts detail the cellular and molecular cascades that cause selective degeneration of neuronal populations, and illuminate those factors that are critical to the facilitation or suppression of these neuropathologic Recent scientific advances have dramatically expanded our understanding of the molecular, genetic, and environmental factors that either cause or contribute to a wide variety of age-related neurodegenerative disorders. In Pathogenesis of Neurodegenerative Disorders, leading experts detail the cellular and molecular cascades that cause selective degeneration of neuronal populations, and illuminate those factors that are critical to the facilitation or suppression of these neuropathologic processes. Working from studies of human patients, as well as from cell culture and animal models, the authors demonstrate a heretofore unrecognized convergence of the causative pathogenetic mechanisms for many clinically distinct neurological disorders. At center stage are the biochemical and molecular cascades that will ultimately lead to neuronal death-cascades involving oxyradical production, aberrant regulation of cellular ion homeostasis, activation of specific proteases, and activation of a stereotyped sequence of events involving mihondrial dysfunction. Individual chapters examine how these mechanisms-along with genetic and environmental factors-operate in Alzheimer's and Parkinson's diseases, Down's syndrome, amyotropic lateral sclerosis, ischemic stroke, spinal cord injury, and Duchenne muscular dystrophy. Pioneering and richly insightful, Pathogenesis of Neurodegenerative Disorders offers a critical and integrative summary of the cutting-edge research findings that illuminate the common genetic, cellular, and molecular bases of many neurological disorders today that promise powerful new preventive and treatment approaches in future. Textbooks New, Books~~Professional Medical & Health Sciences~~Neuroscience - General, Pathogenesis-Of-Neurodegenerative-Disorders~~Mark-P-Mattson, 999999999, Pathogenesis of Neurodegenerative Disorders, Mark P. Mattson (Editor), 0896038386, Springer-Verlag New York, LLC, , , , , Springer-Verlag New York, LLC

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2001, ISBN: 0896038386

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[EAN: 9780896038387], Neubuch, [PU: Humana Press Inc., United States], Language: English Brand New Book ***** Print on Demand *****. As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer s, Parkinson s, and Huntington s diseases. Rapid advances in our understanding of the molecular genetics and environmental factors that either cause or increase risk for age-related neurodegenerative disor- ders have been made in the past decade. The ability to evaluate, at the cellular and molecular level, abnormalities in postmortem brain tissue from patients, when taken together with the development of valuable animal and cell-culture models of neurodegenerative disorders has allowed the identification of sequences of events within neurons that result in their demise in specific neurodegenerative disorders. Though the genetic and environmental factors that pro- mote neurodegeneration may differ among disorders, shared biochemical cascades that will ultimately lead to the death of neurons have been identified. These cascades involve oxyradical production, aberrant regulation of cellular ion homeostasis and activation of a stereotyped sequence of events involving mitochondrial dysfunction and activa- tion of specific proteases. Pathogenesis of Neurodegenerative Disorders provides a timely compilation of articles that encompasses fundamental mechanisms involved in neurodegenerative disorders. In addition, mechanisms that may prevent age-related neurodegenerative disorders are presented. Each chapter is written by an expert in the particular neurodegenerative disorder or mechanism or neuronal death discussed.

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Pathogenesis of Neurodegenerative Disorders. Contemporary Neuroscience. - Mattson, Mark P.
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Erscheinungsjahr: 2001., Verlag/Ort: Totowa, Humana Press, first Edition 294 S. Gr. 8°, Hardcover ISBN: 9780896038387. good condition

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2001, ISBN: 9780896038387

ID: 643781960

Yr. of Pub.2001 089106091X

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Details zum Buch
Pathogenesis of Neurodegenerative Disorders
Autor:

Mattson, Mark P. (ed.)

Titel:

Pathogenesis of Neurodegenerative Disorders

ISBN-Nummer:

0896038386

Mechanisms of Neuronal Apoptosis and Excitotoxicity. Oxidative Alterations in Neurodegenerative Diseases. Parkinson's Disease. Scope of Trinucleotide Repeat Disorders. Mechanisms of Neuronal Death in Huntington's Disease. Cellular and Molecular Mechanisms Underlying Synaptic Degeneration and Neuronal Death in Alzheimer's Disease. Oxidative Stress in Down Syndrome: A Paradigm for the Pathogenesis of Neurodegenerative Disorders. The Pathogenesis of Amyotrophic Lateral Sclerosis. Experimental Genetics as a Tool for Understanding Pathogenesis of ALS. Pathogenesis of Ischemic Stroke. Spinal-Cord Injury. The Pathogenesis of Duchenne Muscular Dystrophy. Index.

Detailangaben zum Buch - Pathogenesis of Neurodegenerative Disorders


EAN (ISBN-13): 9780896038387
ISBN (ISBN-10): 0896038386
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2001
Herausgeber: SPRINGER VERLAG GMBH
304 Seiten
Gewicht: 0,794 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 10.03.2009 17:42:49
Buch zuletzt gefunden am 26.06.2015 12:52:23
ISBN/EAN: 0896038386

ISBN - alternative Schreibweisen:
0-89603-838-6, 978-0-89603-838-7

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