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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad - Chuang Li, Albert P. Lu
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Chuang Li, Albert P. Lu:

Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad - neues Buch

ISBN: 9780470281741

ID: 8dcf9d06139874e7bdd7ae973167b69f

This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both pharmacology and pharmacokinetic aspects of enzyme inhibition. The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development. With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the "good" inhibitions--desirable pharmacological effects--and "bad" inhibitions--drug-drug interactions and toxicity. The book discusses: * The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment * The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug-drug interactions * The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK. Bücher / Fremdsprachige Bücher / Englische Bücher 978-0-470-28174-1, Wiley John + Sons

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Enzyme Inhibition in Drug Discovery and Development. The Good and the Bad - Chuang Lu, Albert P. Li
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Enzyme Inhibition in Drug Discovery and Development. The Good and the Bad - neues Buch

2010, ISBN: 047028174X

ID: 7531303983

[EAN: 9780470281741], Neubuch, [PU: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd), Chicester], Language: english. This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both pharmacology and pharmacokinetic aspects of enzyme inhibition.

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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad - Lu, Chuang (Editor)/ Li, Albert P. (Editor)
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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad - Erstausgabe

2010, ISBN: 047028174X

Gebundene Ausgabe, ID: 12321657438

[EAN: 9780470281741], Neubuch, [PU: John Wiley & Sons Inc], 1st edition. 854 pages. 10.00x6.25x1.75 inches. In Stock.

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2010, ISBN: 9780470281741

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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad
Autor:

Lu, Chuang (EDT)/ Li, Albert P. (EDT)

Titel:

Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad

ISBN-Nummer:

047028174X

The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development. With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the "good" inhibitions--desirable pharmacological effects--and "bad" inhibitions--drug-drug interactions and toxicity. The book discusses: * The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment * The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug-drug interactions * The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK.

Detailangaben zum Buch - Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad


EAN (ISBN-13): 9780470281741
ISBN (ISBN-10): 047028174X
Gebundene Ausgabe
Erscheinungsjahr: 2010
Herausgeber: John Wiley & Sons
854 Seiten
Gewicht: 1,270 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 19.08.2010 12:13:25
Buch zuletzt gefunden am 01.12.2016 06:47:35
ISBN/EAN: 047028174X

ISBN - alternative Schreibweisen:
0-470-28174-X, 978-0-470-28174-1

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